Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.

Excess mortality among patients with severe mental disorders has not previously been investigated in detail in large complete national populations.To investigate the excess mortality in different diagnostic categories due to suicide and other external causes of death, and due to specific causes in c...

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Main Authors: Merete Nordentoft, Kristian Wahlbeck, Jonas Hällgren, Jeanette Westman, Urban Osby, Hassan Alinaghizadeh, Mika Gissler, Thomas Munk Laursen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3555866?pdf=render
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author Merete Nordentoft
Kristian Wahlbeck
Jonas Hällgren
Jeanette Westman
Urban Osby
Hassan Alinaghizadeh
Mika Gissler
Thomas Munk Laursen
author_facet Merete Nordentoft
Kristian Wahlbeck
Jonas Hällgren
Jeanette Westman
Urban Osby
Hassan Alinaghizadeh
Mika Gissler
Thomas Munk Laursen
author_sort Merete Nordentoft
collection DOAJ
description Excess mortality among patients with severe mental disorders has not previously been investigated in detail in large complete national populations.To investigate the excess mortality in different diagnostic categories due to suicide and other external causes of death, and due to specific causes in connection with diseases and medical conditions.In longitudinal national psychiatric case registers from Denmark, Finland, and Sweden, a cohort of 270,770 recent-onset patients, who at least once during the period 2000 to 2006 were admitted due to a psychiatric disorder, were followed until death or the end of 2006. They were followed for 912,279 person years, and 28,088 deaths were analyzed. Life expectancy and standardized cause-specific mortality rates were estimated in each diagnostic group in all three countries.The life expectancy was generally approximately 15 years shorter for women and 20 years shorter for men, compared to the general population. Mortality due to diseases and medical conditions was increased two- to three-fold, while excess mortality from external causes ranged from three- to 77-fold. Mortality due to diseases and medical conditions was generally lowest in patients with affective disorders and highest in patients with substance abuse and personality disorders, while mortality due to suicide was highest in patients with affective disorders and personality disorders, and mortality due to other external causes was highest in patients with substance abuse.These alarming figures call for action in order to prevent the high mortality.
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spelling doaj.art-483b64a7e5d34efa8031e62365b8358a2022-12-21T23:15:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0181e5517610.1371/journal.pone.0055176Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.Merete NordentoftKristian WahlbeckJonas HällgrenJeanette WestmanUrban OsbyHassan AlinaghizadehMika GisslerThomas Munk LaursenExcess mortality among patients with severe mental disorders has not previously been investigated in detail in large complete national populations.To investigate the excess mortality in different diagnostic categories due to suicide and other external causes of death, and due to specific causes in connection with diseases and medical conditions.In longitudinal national psychiatric case registers from Denmark, Finland, and Sweden, a cohort of 270,770 recent-onset patients, who at least once during the period 2000 to 2006 were admitted due to a psychiatric disorder, were followed until death or the end of 2006. They were followed for 912,279 person years, and 28,088 deaths were analyzed. Life expectancy and standardized cause-specific mortality rates were estimated in each diagnostic group in all three countries.The life expectancy was generally approximately 15 years shorter for women and 20 years shorter for men, compared to the general population. Mortality due to diseases and medical conditions was increased two- to three-fold, while excess mortality from external causes ranged from three- to 77-fold. Mortality due to diseases and medical conditions was generally lowest in patients with affective disorders and highest in patients with substance abuse and personality disorders, while mortality due to suicide was highest in patients with affective disorders and personality disorders, and mortality due to other external causes was highest in patients with substance abuse.These alarming figures call for action in order to prevent the high mortality.http://europepmc.org/articles/PMC3555866?pdf=render
spellingShingle Merete Nordentoft
Kristian Wahlbeck
Jonas Hällgren
Jeanette Westman
Urban Osby
Hassan Alinaghizadeh
Mika Gissler
Thomas Munk Laursen
Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
PLoS ONE
title Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
title_full Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
title_fullStr Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
title_full_unstemmed Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
title_short Excess mortality, causes of death and life expectancy in 270,770 patients with recent onset of mental disorders in Denmark, Finland and Sweden.
title_sort excess mortality causes of death and life expectancy in 270 770 patients with recent onset of mental disorders in denmark finland and sweden
url http://europepmc.org/articles/PMC3555866?pdf=render
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