Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
Brucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline pl...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Bilimsel Tip Yayinevi
2002-03-01
|
Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
Subjects: | |
Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdf |
_version_ | 1797906806227337216 |
---|---|
author | Ayşe ERBAY Sebahat T. MEMİŞ Nurcan BAYKAM Başak DOKUZOĞUZ |
author_facet | Ayşe ERBAY Sebahat T. MEMİŞ Nurcan BAYKAM Başak DOKUZOĞUZ |
author_sort | Ayşe ERBAY |
collection | DOAJ |
description | Brucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline plus rifampin versus rifampin plus trimethoprim-sulfamethoxazole combinations. No statistically significant difference was found between the two regimens but early clinical response was observed in rifampin plus trimethoprim sulfamethoxazole combination. |
first_indexed | 2024-04-10T10:27:29Z |
format | Article |
id | doaj.art-483cd6e4b5ca4fca8ae26b1fae4e76a2 |
institution | Directory Open Access Journal |
issn | 1300-932X 1300-932X |
language | English |
last_indexed | 2024-04-10T10:27:29Z |
publishDate | 2002-03-01 |
publisher | Bilimsel Tip Yayinevi |
record_format | Article |
series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
spelling | doaj.art-483cd6e4b5ca4fca8ae26b1fae4e76a22023-02-15T16:21:19ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2002-03-01714448Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of BrucellosisAyşe ERBAY0Sebahat T. MEMİŞ1Nurcan BAYKAM2Başak DOKUZOĞUZ3Ankara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARABrucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline plus rifampin versus rifampin plus trimethoprim-sulfamethoxazole combinations. No statistically significant difference was found between the two regimens but early clinical response was observed in rifampin plus trimethoprim sulfamethoxazole combination.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdfBrucellosisTreatment |
spellingShingle | Ayşe ERBAY Sebahat T. MEMİŞ Nurcan BAYKAM Başak DOKUZOĞUZ Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Brucellosis Treatment |
title | Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis |
title_full | Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis |
title_fullStr | Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis |
title_full_unstemmed | Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis |
title_short | Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis |
title_sort | comparison of efficacy and safety of doxycycline rifampin combination versus rifampin trimethoprim sulfamethoxazole combination in the treatment of brucellosis |
topic | Brucellosis Treatment |
url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdf |
work_keys_str_mv | AT ayseerbay comparisonofefficacyandsafetyofdoxycyclinerifampincombinationversusrifampintrimethoprimsulfamethoxazolecombinationinthetreatmentofbrucellosis AT sebahattmemis comparisonofefficacyandsafetyofdoxycyclinerifampincombinationversusrifampintrimethoprimsulfamethoxazolecombinationinthetreatmentofbrucellosis AT nurcanbaykam comparisonofefficacyandsafetyofdoxycyclinerifampincombinationversusrifampintrimethoprimsulfamethoxazolecombinationinthetreatmentofbrucellosis AT basakdokuzoguz comparisonofefficacyandsafetyofdoxycyclinerifampincombinationversusrifampintrimethoprimsulfamethoxazolecombinationinthetreatmentofbrucellosis |