Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis

Brucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline pl...

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Main Authors: Ayşe ERBAY, Sebahat T. MEMİŞ, Nurcan BAYKAM, Başak DOKUZOĞUZ
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2002-03-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
Online Access:http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdf
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author Ayşe ERBAY
Sebahat T. MEMİŞ
Nurcan BAYKAM
Başak DOKUZOĞUZ
author_facet Ayşe ERBAY
Sebahat T. MEMİŞ
Nurcan BAYKAM
Başak DOKUZOĞUZ
author_sort Ayşe ERBAY
collection DOAJ
description Brucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline plus rifampin versus rifampin plus trimethoprim-sulfamethoxazole combinations. No statistically significant difference was found between the two regimens but early clinical response was observed in rifampin plus trimethoprim sulfamethoxazole combination.
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spelling doaj.art-483cd6e4b5ca4fca8ae26b1fae4e76a22023-02-15T16:21:19ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2002-03-01714448Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of BrucellosisAyşe ERBAY0Sebahat T. MEMİŞ1Nurcan BAYKAM2Başak DOKUZOĞUZ3Ankara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARAAnkara Numune Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, ANKARABrucellosis is a zoonosis existing worldwide. Although a variety of combinations of drugs have been used in the treatment of brucellosis, the best regimen has not been clearly determined. In our study 50 cases of acute brucellosis were examined prospectively to compare the efficacy of doxycycline plus rifampin versus rifampin plus trimethoprim-sulfamethoxazole combinations. No statistically significant difference was found between the two regimens but early clinical response was observed in rifampin plus trimethoprim sulfamethoxazole combination.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdfBrucellosisTreatment
spellingShingle Ayşe ERBAY
Sebahat T. MEMİŞ
Nurcan BAYKAM
Başak DOKUZOĞUZ
Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Brucellosis
Treatment
title Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
title_full Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
title_fullStr Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
title_full_unstemmed Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
title_short Comparison of Efficacy and Safety of Doxycycline + Rifampin Combination Versus Rifampin + Trimethoprim-Sulfamethoxazole Combination in the Treatment of Brucellosis
title_sort comparison of efficacy and safety of doxycycline rifampin combination versus rifampin trimethoprim sulfamethoxazole combination in the treatment of brucellosis
topic Brucellosis
Treatment
url http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-1-044-048.pdf
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