The Colorectal Cancer Microbiota Alter Their Transcriptome To Adapt to the Acidity, Reactive Oxygen Species, and Metabolite Availability of Gut Microenvironments
ABSTRACT The gut microbiome is implicated in the pathology of colorectal cancer (CRC). However, the mechanisms by which the microbiota actively contribute to disease onset and progression remain elusive. In this pilot study, we sequenced fecal metatranscriptomes of 10 non-CRC and 10 CRC patient gut...
Main Authors: | Matthew T. F. Lamaudière, Ramesh Arasaradnam, Gareth D. Weedall, Igor Y. Morozov |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-04-01
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Series: | mSphere |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/msphere.00627-22 |
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