Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...

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Bibliographic Details
Main Authors: Valentina Benedetti, Valerio Brizi, Patrizia Guida, Susanna Tomasoni, Osele Ciampi, Elena Angeli, Ugo Valbusa, Ariela Benigni, Giuseppe Remuzzi, Christodoulos Xinaris
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641830207X

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