Self-organising human gonads generated by a Matrigel-based gradient system

Self-organising human gonads generated by a Matrigel-based gradient system

Abstract Background Advances in three-dimensional culture technologies have led to progression in systems used to model the gonadal microenvironment in vitro. Despite demonstrating basic functionality, tissue organisation is often limited. We have previously detailed a three-dimensional culture mode...

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Bibliographic Details
Main Authors: Elizabeth Oliver, João Pedro Alves-Lopes, Femke Harteveld, Rod T. Mitchell, Elisabet Åkesson, Olle Söder, Jan-Bernd Stukenborg
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Biology
Subjects:
Testis
Ovary
Organoids
Development
Germ cells
Leydig cells
Online Access:https://doi.org/10.1186/s12915-021-01149-3

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