The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies
<i>Background and Objectives</i>: Magnetic resonance imaging (MRI) and the Prostate Imaging-Reporting and Data System (PI-RADS) have become essential tools for prostate cancer evaluation. We evaluated the ability of PI-RADS scores in identifying significant prostate cancer, which would h...
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MDPI AG
2021-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/57/5/413 |
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| author | Dong-Soo Kim Sung-Kyoung Moon Joo-Won Lim Seung-Hyun Jeon Sang-Hyub Lee |
| author_facet | Dong-Soo Kim Sung-Kyoung Moon Joo-Won Lim Seung-Hyun Jeon Sang-Hyub Lee |
| author_sort | Dong-Soo Kim |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Magnetic resonance imaging (MRI) and the Prostate Imaging-Reporting and Data System (PI-RADS) have become essential tools for prostate cancer evaluation. We evaluated the ability of PI-RADS scores in identifying significant prostate cancer, which would help avoid unnecessary prostate biopsies. <i>Materials and Methods</i>: Patients with prostate-specific antigen (PSA) levels ≤ 20 ng/mL, who underwent prostate MRI for evaluation from January 2018 to November 2019, were analyzed. Among them, 105 patients who received transrectal ultrasonography (TRUS)-guided biopsy were included. PSA, PI-RADS scores (low 1–2, high 3–5), biopsy results, and Gleason scores (GS) were evaluated. Biopsies with GS higher than 3 + 4 were considered as significant cancers and biopsies with no cancer or Gleason 3 + 3 were considered insignificant or no cancers. <i>Results</i>: Among the 105 patients, 45 patients had low PI-RADS and 60 had high PI-RADS scores. There were no patients with significant prostate cancer in the low PI-RADS groups. For the high PI-RADS group, 28 (46.7%) patients had significant cancer and 32 (53.3%) had insignificant or no cancer. The sensitivity and specificity of high PI-RADS to detect significant cancer was 100% and 58.4%, respectively. Positive predictive value was 46.7% and negative predictive value was 100%. <i>Conclusions</i>: Low PI-RADS scores on MRI did not show significant prostate cancer and surveillance should be considered in selected cases to prevent unnecessary invasive procedures and overdiagnosis. |
| first_indexed | 2024-03-10T12:00:45Z |
| format | Article |
| id | doaj.art-484961cc188e48dd9468d7ed79c7d79b |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T12:00:45Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-484961cc188e48dd9468d7ed79c7d79b2023-11-21T16:59:13ZengMDPI AGMedicina1010-660X1648-91442021-04-0157541310.3390/medicina57050413The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate BiopsiesDong-Soo Kim0Sung-Kyoung Moon1Joo-Won Lim2Seung-Hyun Jeon3Sang-Hyub Lee4Department of Urology, Kyung Hee University School of Medicine, Seoul 02453, KoreaDepartment of Radiology, Kyung Hee University School of Medicine, Seoul 02453, KoreaDepartment of Radiology, Kyung Hee University School of Medicine, Seoul 02453, KoreaDepartment of Urology, Kyung Hee University School of Medicine, Seoul 02453, KoreaDepartment of Urology, Kyung Hee University School of Medicine, Seoul 02453, Korea<i>Background and Objectives</i>: Magnetic resonance imaging (MRI) and the Prostate Imaging-Reporting and Data System (PI-RADS) have become essential tools for prostate cancer evaluation. We evaluated the ability of PI-RADS scores in identifying significant prostate cancer, which would help avoid unnecessary prostate biopsies. <i>Materials and Methods</i>: Patients with prostate-specific antigen (PSA) levels ≤ 20 ng/mL, who underwent prostate MRI for evaluation from January 2018 to November 2019, were analyzed. Among them, 105 patients who received transrectal ultrasonography (TRUS)-guided biopsy were included. PSA, PI-RADS scores (low 1–2, high 3–5), biopsy results, and Gleason scores (GS) were evaluated. Biopsies with GS higher than 3 + 4 were considered as significant cancers and biopsies with no cancer or Gleason 3 + 3 were considered insignificant or no cancers. <i>Results</i>: Among the 105 patients, 45 patients had low PI-RADS and 60 had high PI-RADS scores. There were no patients with significant prostate cancer in the low PI-RADS groups. For the high PI-RADS group, 28 (46.7%) patients had significant cancer and 32 (53.3%) had insignificant or no cancer. The sensitivity and specificity of high PI-RADS to detect significant cancer was 100% and 58.4%, respectively. Positive predictive value was 46.7% and negative predictive value was 100%. <i>Conclusions</i>: Low PI-RADS scores on MRI did not show significant prostate cancer and surveillance should be considered in selected cases to prevent unnecessary invasive procedures and overdiagnosis.https://www.mdpi.com/1648-9144/57/5/413prostate cancermultiparametric magnetic resonance imagingimage-guided biopsyprostate specific antigencancer screening |
| spellingShingle | Dong-Soo Kim Sung-Kyoung Moon Joo-Won Lim Seung-Hyun Jeon Sang-Hyub Lee The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies Medicina prostate cancer multiparametric magnetic resonance imaging image-guided biopsy prostate specific antigen cancer screening |
| title | The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies |
| title_full | The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies |
| title_fullStr | The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies |
| title_full_unstemmed | The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies |
| title_short | The Value of Low Prostate Imaging—Reporting and Data System (PI-RADS) Scores in Preventing Unnecessary Prostate Biopsies |
| title_sort | value of low prostate imaging reporting and data system pi rads scores in preventing unnecessary prostate biopsies |
| topic | prostate cancer multiparametric magnetic resonance imaging image-guided biopsy prostate specific antigen cancer screening |
| url | https://www.mdpi.com/1648-9144/57/5/413 |
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