Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection
The insula is involved in a wide variety of functions, including social and emotional processing. Despite the numerous connections it shares with brain structures known to play a role in autobiographical memory (AM), little is known on the contribution of the insula to AM processing. The aim of the...
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MDPI AG
2021-10-01
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| Online Access: | https://www.mdpi.com/2076-3425/11/10/1316 |
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| author | Mélanie Descamps Olivier Boucher Dang Khoa Nguyen Isabelle Rouleau |
| author_facet | Mélanie Descamps Olivier Boucher Dang Khoa Nguyen Isabelle Rouleau |
| author_sort | Mélanie Descamps |
| collection | DOAJ |
| description | The insula is involved in a wide variety of functions, including social and emotional processing. Despite the numerous connections it shares with brain structures known to play a role in autobiographical memory (AM), little is known on the contribution of the insula to AM processing. The aim of the study was to examine emotional AM retrieval in patients with insular resection for drug-resistant epilepsy. Ten patients who underwent partial or complete insular resection (IR) were matched on age, sex, and education, to fifteen patients who underwent temporal lobectomy (TL), and to fifteen healthy controls. Participants were asked to recall four positive, four negative, and four neutral memories from their past using the autobiographical interview procedure. The results suggest that AM for emotional and neutral events after IR was comparable to that of healthy controls, whereas deficits were observed after TL. However, an independent examiner judged IR patients’ memories as poorer than those of healthy controls on the episodic richness scale, suggesting a lack of some aspects of rich and vivid remembering. Furthermore, analysis on subjective self-rated scales revealed that, contrary to healthy controls, patients with IR judged their neutral memories as more emotional. This study suggests that AM is generally preserved after IR. However, given the small sample size and varied lesion location, one cannot totally exclude a potential role of specific insular sub-regions on some aspects of autobiographical memory. In addition, IR patients showed poor emotional judgment for neutral memories, which is congruent with previous findings of altered emotional processing in this population. |
| first_indexed | 2024-03-10T06:41:18Z |
| format | Article |
| id | doaj.art-4849eda15994495c935eb65648bae2b8 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T06:41:18Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
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| series | Brain Sciences |
| spelling | doaj.art-4849eda15994495c935eb65648bae2b82023-11-22T17:37:18ZengMDPI AGBrain Sciences2076-34252021-10-011110131610.3390/brainsci11101316Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe ResectionMélanie Descamps0Olivier Boucher1Dang Khoa Nguyen2Isabelle Rouleau3Département de psychologie, Université du Québec à Montréal, Montreal, QC H2X 3P2, CanadaCentre de recherche du Centre Hospitalier de l’Université de Montréal, Montreal, QC H2X 0A9, CanadaCentre de recherche du Centre Hospitalier de l’Université de Montréal, Montreal, QC H2X 0A9, CanadaDépartement de psychologie, Université du Québec à Montréal, Montreal, QC H2X 3P2, CanadaThe insula is involved in a wide variety of functions, including social and emotional processing. Despite the numerous connections it shares with brain structures known to play a role in autobiographical memory (AM), little is known on the contribution of the insula to AM processing. The aim of the study was to examine emotional AM retrieval in patients with insular resection for drug-resistant epilepsy. Ten patients who underwent partial or complete insular resection (IR) were matched on age, sex, and education, to fifteen patients who underwent temporal lobectomy (TL), and to fifteen healthy controls. Participants were asked to recall four positive, four negative, and four neutral memories from their past using the autobiographical interview procedure. The results suggest that AM for emotional and neutral events after IR was comparable to that of healthy controls, whereas deficits were observed after TL. However, an independent examiner judged IR patients’ memories as poorer than those of healthy controls on the episodic richness scale, suggesting a lack of some aspects of rich and vivid remembering. Furthermore, analysis on subjective self-rated scales revealed that, contrary to healthy controls, patients with IR judged their neutral memories as more emotional. This study suggests that AM is generally preserved after IR. However, given the small sample size and varied lesion location, one cannot totally exclude a potential role of specific insular sub-regions on some aspects of autobiographical memory. In addition, IR patients showed poor emotional judgment for neutral memories, which is congruent with previous findings of altered emotional processing in this population.https://www.mdpi.com/2076-3425/11/10/1316autobiographical memoryemotioninsulatemporal lobeepilepsyneurosurgery |
| spellingShingle | Mélanie Descamps Olivier Boucher Dang Khoa Nguyen Isabelle Rouleau Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection Brain Sciences autobiographical memory emotion insula temporal lobe epilepsy neurosurgery |
| title | Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection |
| title_full | Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection |
| title_fullStr | Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection |
| title_full_unstemmed | Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection |
| title_short | Emotional Autobiographical Memory Associated with Insular Resection in Epileptic Patients: A Comparison with Temporal Lobe Resection |
| title_sort | emotional autobiographical memory associated with insular resection in epileptic patients a comparison with temporal lobe resection |
| topic | autobiographical memory emotion insula temporal lobe epilepsy neurosurgery |
| url | https://www.mdpi.com/2076-3425/11/10/1316 |
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