Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study

Abstract Objective Neonatal sepsis still remains a significant cause of morbidity and mortality in developing countries. The prediction of the neonatal sepsis outcome depends on the anticipation from the clinical history, suspicion from clinical findings and confirmation by laboratory tests. This st...

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Main Authors: Gabriel Kambale Bunduki, Yaw Adu-Sarkodie
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-019-4346-5
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author Gabriel Kambale Bunduki
Yaw Adu-Sarkodie
author_facet Gabriel Kambale Bunduki
Yaw Adu-Sarkodie
author_sort Gabriel Kambale Bunduki
collection DOAJ
description Abstract Objective Neonatal sepsis still remains a significant cause of morbidity and mortality in developing countries. The prediction of the neonatal sepsis outcome depends on the anticipation from the clinical history, suspicion from clinical findings and confirmation by laboratory tests. This study aimed to determine the clinical outcome and isolated pathogens among neonates with sepsis in Butembo, Democratic Republic of the Congo. Results The most frequent bacteria related to a poor outcome were Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella spp. Most of isolated bacteria were found to be hospital-acquired infections. Therefore, adherence to infection prevention and control measures would reduce reduced rate of neonatal sepsis in our setting. The empiric antibiotic treatment should cover the spectrum of bacteria responsible of neonatal sepsis in Butembo, DRC.
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spelling doaj.art-4850c9ba56d5445bac9e646c6f88fba42022-12-21T18:58:34ZengBMCBMC Research Notes1756-05002019-05-011211510.1186/s13104-019-4346-5Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional studyGabriel Kambale Bunduki0Yaw Adu-Sarkodie1Department of Infectious Diseases, Faculty of Medicine, Université Catholique du GrabenDepartment of Clinical Microbiology, School of Medical Sciences, College of Medicine, Kwame Nkrumah University of Science and TechnologyAbstract Objective Neonatal sepsis still remains a significant cause of morbidity and mortality in developing countries. The prediction of the neonatal sepsis outcome depends on the anticipation from the clinical history, suspicion from clinical findings and confirmation by laboratory tests. This study aimed to determine the clinical outcome and isolated pathogens among neonates with sepsis in Butembo, Democratic Republic of the Congo. Results The most frequent bacteria related to a poor outcome were Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella spp. Most of isolated bacteria were found to be hospital-acquired infections. Therefore, adherence to infection prevention and control measures would reduce reduced rate of neonatal sepsis in our setting. The empiric antibiotic treatment should cover the spectrum of bacteria responsible of neonatal sepsis in Butembo, DRC.http://link.springer.com/article/10.1186/s13104-019-4346-5Clinical outcomeRisk factorNeonatal sepsisButemboDRC
spellingShingle Gabriel Kambale Bunduki
Yaw Adu-Sarkodie
Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
BMC Research Notes
Clinical outcome
Risk factor
Neonatal sepsis
Butembo
DRC
title Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
title_full Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
title_fullStr Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
title_full_unstemmed Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
title_short Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
title_sort clinical outcome and isolated pathogens among neonates with sepsis in democratic republic of the congo a cross sectional study
topic Clinical outcome
Risk factor
Neonatal sepsis
Butembo
DRC
url http://link.springer.com/article/10.1186/s13104-019-4346-5
work_keys_str_mv AT gabrielkambalebunduki clinicaloutcomeandisolatedpathogensamongneonateswithsepsisindemocraticrepublicofthecongoacrosssectionalstudy
AT yawadusarkodie clinicaloutcomeandisolatedpathogensamongneonateswithsepsisindemocraticrepublicofthecongoacrosssectionalstudy