Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p

Exosomes derived from synovial fibroblasts from patients with rheumatoid arthritis promote macrophage migration that can be suppressed by miR-124-3p

Objectives: Exosomes are potent vehicles for intercellular communication. Rheumatoid arthritis (RA) is a chronic systemic disease of unknown etiology. Local administration of miR-124 precursor to rats with adjuvant-induced arthritis suppresses systemic arthritis and bone destruction. Thus, exosomes...

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Bibliographic Details
Main Authors:	Yuji Nakamachi, Kenichi Uto, Shinya Hayashi, Takaichi Okano, Akio Morinobu, Ryosuke Kuroda, Seiji Kawano, Jun Saegusa
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Heliyon
Subjects:	Rheumatoid arthritis Fibroblast-like synoviocytes Exosome miR-124-3p Macrophage Migration
Online Access:	http://www.sciencedirect.com/science/article/pii/S240584402302193X

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