Cytokine and Reward Circuitry Relationships in Treatment-Resistant Depression

Cytokine and Reward Circuitry Relationships in Treatment-Resistant Depression

Background: Depressive disorders are linked to dysfunction in reward-related behaviors and corticostriatal reward circuitry. Low-grade dysregulation of the immune system, e.g., elevations in plasma interleukin 6 (IL-6) and tumor necrosis factor α, have been thought to affect corticostriatal reward c...

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Bibliographic Details
Main Authors: Manivel Rengasamy, Lena Brundin, Angela Griffo, Benjamin Panny, Colt Capan, Cameron Forton, Rebecca B. Price
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Biological Psychiatry Global Open Science
Subjects:
Childhood trauma
Circuitry
Corticostriatal
Cytokine
Moderation
Reward
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174321000550

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