Convenient Synthesis of 3,4-Dichloro-5-hydroxy-2(5H)-Furanone Glycoconjugates

Convenient Synthesis of 3,4-Dichloro-5-hydroxy-2(5H)-Furanone Glycoconjugates

3,4-Dichloro-5-hydroxy-2(5H)-furanone treated with methyl chloroformate in the presence of diisopropylethylamine (Hünig’s base) gave the corresponding carbonate. The labile methoxycarbonyloxy group smoothly undergoes substitution by amino alcohols. The obtained 5-(w-hydroxyalkylamino) mucochloric ac...

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Bibliographic Details
Main Authors: Edyta Gondela, Krzysztof Z. Walczak
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Molecules
Subjects:
3,4-dichloromucochloric acid
amino alcohol
glucals
addition
glycoconjugate
Online Access:http://www.mdpi.com/1420-3049/16/2/1011/

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