Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency

Background: Many studies have shown a high prevalence of vitamin D deficiency in different communities. Due to multiple roles of vitamin D in the body, this study was aimed to determine the effect of oral vitamin D3 on ventilatory threshold-1 in a condition of vitamin D deficiency. Materials and Met...

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Main Authors: Amir Safarzadeh, Mehrshad Poursaeid Esfahani, Amir Hossein Abedi Yekta, Shahin Salehi, Mohammad Hassabi
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2019-01-01
Series:Novelty in Biomedicine
Subjects:
Online Access:http://journals.sbmu.ac.ir/nbm/article/view/23048
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author Amir Safarzadeh
Mehrshad Poursaeid Esfahani
Amir Hossein Abedi Yekta
Shahin Salehi
Mohammad Hassabi
author_facet Amir Safarzadeh
Mehrshad Poursaeid Esfahani
Amir Hossein Abedi Yekta
Shahin Salehi
Mohammad Hassabi
author_sort Amir Safarzadeh
collection DOAJ
description Background: Many studies have shown a high prevalence of vitamin D deficiency in different communities. Due to multiple roles of vitamin D in the body, this study was aimed to determine the effect of oral vitamin D3 on ventilatory threshold-1 in a condition of vitamin D deficiency. Materials and Methods: Recent study performed on 25 healthy young adults with the serum levels of 25 Hydroxyvitamin D3 lower than 20 ng/ml, had referred to the sports medicine clinic of Taleghani Hospital of Tehran, in a one-year period (2016-2017). After primary evaluation, baseline ventilatory threshold-1 were determined by cardiopulmonary exercise testing (CPET). Then persons were treated with 50,000 IU/week of oral vitamin D3 for 8 weeks, and one week after the completion of treatment, ventilator threshold-1 was measured again, similar to the beginning conditions of the study, and its changes were studied. Results: The mean baseline ventilatory threshold-1 of participants before any intervention was 22.46 ± 6.45 (ml/kg/min), and after 8 weeks of treatment by 50000 IU/week of oral vitamin D3, increased to 26.79 ± 5.33 (ml/kg/min) at the end of study, which there was a statistically significant increase in ventilatory threshold-1 (p<0.001). Conclusion: Recent study showed that proper treatment of the vitamin D deficiency, improves ventilatory threshold-1 in healthy young adults.
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spelling doaj.art-485cb79978d64863b94f33482140900f2022-12-21T19:57:12ZengShahid Beheshti University of Medical SciencesNovelty in Biomedicine2345-33462345-39072019-01-0171172310.22037/nbm.v7i1.2304811457Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D DeficiencyAmir Safarzadeh0Mehrshad Poursaeid Esfahani1Amir Hossein Abedi Yekta2Shahin Salehi3Mohammad Hassabi4Department of the sports medicine of Taleghani hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of the sports medicine of Taleghani hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of the sports medicine of Taleghani hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of the sports medicine of Taleghani hospital, Shahid Beheshti University of Medical Science, Tehran, IranDepartment of the sports medicine of Taleghani hospital, Shahid Beheshti University of Medical Science, Tehran, IranBackground: Many studies have shown a high prevalence of vitamin D deficiency in different communities. Due to multiple roles of vitamin D in the body, this study was aimed to determine the effect of oral vitamin D3 on ventilatory threshold-1 in a condition of vitamin D deficiency. Materials and Methods: Recent study performed on 25 healthy young adults with the serum levels of 25 Hydroxyvitamin D3 lower than 20 ng/ml, had referred to the sports medicine clinic of Taleghani Hospital of Tehran, in a one-year period (2016-2017). After primary evaluation, baseline ventilatory threshold-1 were determined by cardiopulmonary exercise testing (CPET). Then persons were treated with 50,000 IU/week of oral vitamin D3 for 8 weeks, and one week after the completion of treatment, ventilator threshold-1 was measured again, similar to the beginning conditions of the study, and its changes were studied. Results: The mean baseline ventilatory threshold-1 of participants before any intervention was 22.46 ± 6.45 (ml/kg/min), and after 8 weeks of treatment by 50000 IU/week of oral vitamin D3, increased to 26.79 ± 5.33 (ml/kg/min) at the end of study, which there was a statistically significant increase in ventilatory threshold-1 (p<0.001). Conclusion: Recent study showed that proper treatment of the vitamin D deficiency, improves ventilatory threshold-1 in healthy young adults.http://journals.sbmu.ac.ir/nbm/article/view/2304825 Hydroxyvitamin D3, Anaerobic Threshold, Vitamin D deficiency
spellingShingle Amir Safarzadeh
Mehrshad Poursaeid Esfahani
Amir Hossein Abedi Yekta
Shahin Salehi
Mohammad Hassabi
Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
Novelty in Biomedicine
25 Hydroxyvitamin D3, Anaerobic Threshold, Vitamin D deficiency
title Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
title_full Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
title_fullStr Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
title_full_unstemmed Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
title_short Determination of Effect of Oral Vitamin D to Improve Ventilatory Threshold in Healthy Young Adults with Vitamin D Deficiency
title_sort determination of effect of oral vitamin d to improve ventilatory threshold in healthy young adults with vitamin d deficiency
topic 25 Hydroxyvitamin D3, Anaerobic Threshold, Vitamin D deficiency
url http://journals.sbmu.ac.ir/nbm/article/view/23048
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