Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants

The aim. This study aims to determine the reintervention rate in infantsundergoing aortic arch repair and to analyze risk factors and evaluate the results of reinterventions. Materials and methods. This retrospective study examines 445 infants with aortic arch hypoplasia who under-went aortic arc...

Full description

Bibliographic Details
Main Authors: Iaroslav P. Truba, Oleksandr S. Golovenko, Ivan V. Dziuryi
Format: Article
Language:English
Published: Professional Edition Eastern Europe 2022-12-01
Series:Український журнал серцево-судинної хірургії
Subjects:
Online Access:http://cvs.org.ua/index.php/ujcvs/article/view/528
_version_ 1797974470707642368
author Iaroslav P. Truba
Oleksandr S. Golovenko
Ivan V. Dziuryi
author_facet Iaroslav P. Truba
Oleksandr S. Golovenko
Ivan V. Dziuryi
author_sort Iaroslav P. Truba
collection DOAJ
description The aim. This study aims to determine the reintervention rate in infantsundergoing aortic arch repair and to analyze risk factors and evaluate the results of reinterventions. Materials and methods. This retrospective study examines 445 infants with aortic arch hypoplasia who under-went aortic arch reconstruction between 2011 and 2019. The study included only patients with two-ventricle physiology and subsequent two-ventricle repair. Techniques for primary repair included extended end-to-end anastomosis (n = 348), end-to-side anastomosis (n = 611), autologous pericardial patch repair (n = 16). Results. The overall mortality in the entire study group was 3.3 %. Follow-up period ranged from 1 month to 9.4 years (mean 2.8 ± 2.5 years). Restenosis at the site of aortic arch repair was identiϐied in 47 (10.5 %) patients. Of these, 12 patients underwent surgical reconstruction of the aortic arch, 27 patients underwent balloon angioplasty, and in 8 patients both methods were used. Freedom from reintervention was 89.4 % at 1-year follow-up and 87.5 % at 4-year follow-up. The most determining factorsfor restenosis were related to hypoplastic proximal aortic arch and body weight less than 2.5 kg. Conclusions. Surgical treatment of aortic arch hypoplasia in newborns and infants is effective and shows good immediate and long-term results. Anatomical correction of reobstruction at the level of the aortic arch is safe with both endovacular and surgical methods with low mortality and incidence of repeated interventions. Identified risk factors for mortality and recurrent aortic arch interventions help to improve the treatment of aortic arch hypoplasia in patients under 1 year of age.
first_indexed 2024-04-11T04:20:28Z
format Article
id doaj.art-4862038e80cc4c2f9badec6ac7fc8666
institution Directory Open Access Journal
issn 2664-5963
2664-5971
language English
last_indexed 2024-04-11T04:20:28Z
publishDate 2022-12-01
publisher Professional Edition Eastern Europe
record_format Article
series Український журнал серцево-судинної хірургії
spelling doaj.art-4862038e80cc4c2f9badec6ac7fc86662022-12-30T20:34:45ZengProfessional Edition Eastern EuropeУкраїнський журнал серцево-судинної хірургії2664-59632664-59712022-12-01304596510.30702/ujcvs/22.30(04)/TG056-5965528Restenosis Rate and Reinterventions after Aortic Arch Repair in InfantsIaroslav P. Truba0https://orcid.org/0000-0001-5214-408XOleksandr S. Golovenko1https://orcid.org/0000-0001-6002-3325Ivan V. Dziuryi2https://orcid.org/0000-0002-1073-7060National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineNational Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineNational Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, Kyiv, UkraineThe aim. This study aims to determine the reintervention rate in infantsundergoing aortic arch repair and to analyze risk factors and evaluate the results of reinterventions. Materials and methods. This retrospective study examines 445 infants with aortic arch hypoplasia who under-went aortic arch reconstruction between 2011 and 2019. The study included only patients with two-ventricle physiology and subsequent two-ventricle repair. Techniques for primary repair included extended end-to-end anastomosis (n = 348), end-to-side anastomosis (n = 611), autologous pericardial patch repair (n = 16). Results. The overall mortality in the entire study group was 3.3 %. Follow-up period ranged from 1 month to 9.4 years (mean 2.8 ± 2.5 years). Restenosis at the site of aortic arch repair was identiϐied in 47 (10.5 %) patients. Of these, 12 patients underwent surgical reconstruction of the aortic arch, 27 patients underwent balloon angioplasty, and in 8 patients both methods were used. Freedom from reintervention was 89.4 % at 1-year follow-up and 87.5 % at 4-year follow-up. The most determining factorsfor restenosis were related to hypoplastic proximal aortic arch and body weight less than 2.5 kg. Conclusions. Surgical treatment of aortic arch hypoplasia in newborns and infants is effective and shows good immediate and long-term results. Anatomical correction of reobstruction at the level of the aortic arch is safe with both endovacular and surgical methods with low mortality and incidence of repeated interventions. Identified risk factors for mortality and recurrent aortic arch interventions help to improve the treatment of aortic arch hypoplasia in patients under 1 year of age.http://cvs.org.ua/index.php/ujcvs/article/view/528recurrent obstructionballoon angioplastysurgical reconstructionrisk factors for mortalityhypoplasia
spellingShingle Iaroslav P. Truba
Oleksandr S. Golovenko
Ivan V. Dziuryi
Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
Український журнал серцево-судинної хірургії
recurrent obstruction
balloon angioplasty
surgical reconstruction
risk factors for mortality
hypoplasia
title Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
title_full Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
title_fullStr Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
title_full_unstemmed Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
title_short Restenosis Rate and Reinterventions after Aortic Arch Repair in Infants
title_sort restenosis rate and reinterventions after aortic arch repair in infants
topic recurrent obstruction
balloon angioplasty
surgical reconstruction
risk factors for mortality
hypoplasia
url http://cvs.org.ua/index.php/ujcvs/article/view/528
work_keys_str_mv AT iaroslavptruba restenosisrateandreinterventionsafteraorticarchrepairininfants
AT oleksandrsgolovenko restenosisrateandreinterventionsafteraorticarchrepairininfants
AT ivanvdziuryi restenosisrateandreinterventionsafteraorticarchrepairininfants