Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus

Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly heterogeneous clinical symptoms and severity. There is complex pathogenesis of SLE, one of which is IFNs overproduction and downstream IFN-stimulated genes (ISGs) upregulation. Identifying the key ISGs differentially expr...

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Bibliographic Details
Main Authors: Mengjia Shen, Congcong Duan, Changhao Xie, Hongtao Wang, Zhijun Li, Baiqing Li, Tao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
interferon
interferon-stimulated gene
bioinformatics
GEO database
long non-coding RNA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.962393/full

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