The role of Dicer protein partners in the processing of microRNA precursors.
One of the cellular functions of the ribonuclease Dicer is to process microRNA precursors (pre-miRNAs) into mature microRNAs (miRNAs). Human Dicer performs this function in cooperation with its protein partners, AGO2, PACT and TRBP. The exact role of these accessory proteins in Dicer activity is sti...
Main Authors: | Edyta Koscianska, Julia Starega-Roslan, Wlodzimierz J Krzyzosiak |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3232248?pdf=render |
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