Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations
Since the beginning of the pandemic, the new coronavirus infection has been regarded primarily as a respiratory disease. By now, it has become obvious that COVID-19 is a systemic infectious process with multiple organ damage. Having affinity for ACE-2 receptors, the virus can infect the cells of the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2022-11-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/1712 |
| _version_ | 1797875094271295488 |
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| author | V. A. Pozdnyak S. V. Khaliullina V. A. Anokhin |
| author_facet | V. A. Pozdnyak S. V. Khaliullina V. A. Anokhin |
| author_sort | V. A. Pozdnyak |
| collection | DOAJ |
| description | Since the beginning of the pandemic, the new coronavirus infection has been regarded primarily as a respiratory disease. By now, it has become obvious that COVID-19 is a systemic infectious process with multiple organ damage. Having affinity for ACE-2 receptors, the virus can infect the cells of the respiratory tract, as well as the cells of the cardiovascular and nervous systems and smooth muscle structures of various organs. Expression of ACE-2 by enterocytes of the small intestine makes the gastrointestinal tract vulnerable in COVID-19 disease and leads to the manifestation of symptoms of gastrointestinal damage, which is often observed in clinical practice. Gastrointestinal symptoms usually include anorexia, nausea, vomiting, diarrhea, and abdominal pain, which can occur both at the onset and during the disease. Several mechanisms are described to explain these changes in COVID-19. |
| first_indexed | 2024-04-10T01:41:14Z |
| format | Article |
| id | doaj.art-4869b0e88e8749cd9ebc5cbd4cf70223 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:41:14Z |
| publishDate | 2022-11-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-4869b0e88e8749cd9ebc5cbd4cf702232023-03-13T09:12:53ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282022-11-0167512312910.21508/1027-4065-2022-67-5-123-1291251Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestationsV. A. Pozdnyak0S. V. Khaliullina1V. A. Anokhin2ФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Казанский государственный медицинский университет» Минздрава РоссииSince the beginning of the pandemic, the new coronavirus infection has been regarded primarily as a respiratory disease. By now, it has become obvious that COVID-19 is a systemic infectious process with multiple organ damage. Having affinity for ACE-2 receptors, the virus can infect the cells of the respiratory tract, as well as the cells of the cardiovascular and nervous systems and smooth muscle structures of various organs. Expression of ACE-2 by enterocytes of the small intestine makes the gastrointestinal tract vulnerable in COVID-19 disease and leads to the manifestation of symptoms of gastrointestinal damage, which is often observed in clinical practice. Gastrointestinal symptoms usually include anorexia, nausea, vomiting, diarrhea, and abdominal pain, which can occur both at the onset and during the disease. Several mechanisms are described to explain these changes in COVID-19.https://www.ped-perinatology.ru/jour/article/view/1712детиcovid-19желудочно-кишечный трактдиарея |
| spellingShingle | V. A. Pozdnyak S. V. Khaliullina V. A. Anokhin Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations Rossijskij Vestnik Perinatologii i Pediatrii дети covid-19 желудочно-кишечный тракт диарея |
| title | Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations |
| title_full | Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations |
| title_fullStr | Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations |
| title_full_unstemmed | Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations |
| title_short | Gastrointestinal tract lesion in children with COVID-19: from pathogenesis to clinical manifestations |
| title_sort | gastrointestinal tract lesion in children with covid 19 from pathogenesis to clinical manifestations |
| topic | дети covid-19 желудочно-кишечный тракт диарея |
| url | https://www.ped-perinatology.ru/jour/article/view/1712 |
| work_keys_str_mv | AT vapozdnyak gastrointestinaltractlesioninchildrenwithcovid19frompathogenesistoclinicalmanifestations AT svkhaliullina gastrointestinaltractlesioninchildrenwithcovid19frompathogenesistoclinicalmanifestations AT vaanokhin gastrointestinaltractlesioninchildrenwithcovid19frompathogenesistoclinicalmanifestations |