Proteomics of Stored Red Blood Cell Membrane and Storage-Induced Microvesicles Reveals the Association of Flotillin-2 With Band 3 Complexes

Proteomics of Stored Red Blood Cell Membrane and Storage-Induced Microvesicles Reveals the Association of Flotillin-2 With Band 3 Complexes

The storage of erythrocyte concentrates (ECs) induces lesions that notably affect metabolism, protein activity, deformability of red blood cells (RBCs), as well as the release of oxygen. Band 3 is one of the proteins affected during the ex vivo aging of RBCs. This membrane protein is an anion transp...

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Bibliographic Details
Main Authors: Michel Prudent, Julien Delobel, Aurélie Hübner, Corinne Benay, Niels Lion, Jean-Daniel Tissot
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
band 3
flotillin-2
immunoprecipitation
proteomics
red blood cells
storage
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00421/full

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