Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases
Mean corpuscular hemoglobin concentration (MCHC), a parameter that is reported as a part of a standard complete blood count by automated analyzer, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. Values of MCHC significantly above reference range are not ph...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-10-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=4;spage=820;epage=823;aulast=Sharma |
| _version_ | 1818826204032008192 |
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| author | Sharma Sunita Pujani Meenu Pahuja Sangeeta Chandra Jagdish Rath B Labhchand |
| author_facet | Sharma Sunita Pujani Meenu Pahuja Sangeeta Chandra Jagdish Rath B Labhchand |
| author_sort | Sharma Sunita |
| collection | DOAJ |
| description | Mean corpuscular hemoglobin concentration (MCHC), a parameter that is reported as a part of a standard complete blood count by automated analyzer, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. Values of MCHC significantly above reference range are not physiologically possible due to limitations on solubility of hemoglobin. The high MCHC can give us a clue to certain type of hemolytic anemia and necessitate critical evaluation of peripheral smear to reach a definitive diagnosis. Here we are presenting a series of four cases with raised MCHC, emphasizing the importance of systematic and meticulous examination of the peripheral smear to render a definitive diagnosis. |
| first_indexed | 2024-12-19T00:23:56Z |
| format | Article |
| id | doaj.art-486fdc7e74d84eba9717909f807d063f |
| institution | Directory Open Access Journal |
| issn | 0377-4929 0974-5130 |
| language | English |
| last_indexed | 2024-12-19T00:23:56Z |
| publishDate | 2010-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-486fdc7e74d84eba9717909f807d063f2022-12-21T20:45:23ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302010-10-01534820823Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four casesSharma SunitaPujani MeenuPahuja SangeetaChandra JagdishRath BLabhchandMean corpuscular hemoglobin concentration (MCHC), a parameter that is reported as a part of a standard complete blood count by automated analyzer, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. Values of MCHC significantly above reference range are not physiologically possible due to limitations on solubility of hemoglobin. The high MCHC can give us a clue to certain type of hemolytic anemia and necessitate critical evaluation of peripheral smear to reach a definitive diagnosis. Here we are presenting a series of four cases with raised MCHC, emphasizing the importance of systematic and meticulous examination of the peripheral smear to render a definitive diagnosis.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=4;spage=820;epage=823;aulast=SharmaAnemiamean corpuscular hemoglobin concentrationperipheral smear |
| spellingShingle | Sharma Sunita Pujani Meenu Pahuja Sangeeta Chandra Jagdish Rath B Labhchand Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases Indian Journal of Pathology and Microbiology Anemia mean corpuscular hemoglobin concentration peripheral smear |
| title | Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases |
| title_full | Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases |
| title_fullStr | Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases |
| title_full_unstemmed | Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases |
| title_short | Critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children: A series of four cases |
| title_sort | critical evaluation of peripheral smear in cases of anemia with high mean corpuscular hemoglobin concentration in children a series of four cases |
| topic | Anemia mean corpuscular hemoglobin concentration peripheral smear |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=4;spage=820;epage=823;aulast=Sharma |
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