An iron-deficient diet prevents alcohol- or diethylnitrosamine-induced acute hepatotoxicity in mice by inhibiting ferroptosis

An iron-deficient diet prevents alcohol- or diethylnitrosamine-induced acute hepatotoxicity in mice by inhibiting ferroptosis

The liver is easily injured by exogenous chemicals through reactive oxygen species (ROS), which lead to ferroptosis, a ROS-dependent programmed cell death characterized by iron accumulation and lipid peroxidation. However, whether iron restriction has a positive role in chemicals-induced liver injur...

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Bibliographic Details
Main Authors: Zelong Gao, Dongyao Wang, Hongwei Zhang, Jianxin Yang, Min Li, Hongtao Lu, Hui Shen, Yuxiao Tang
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Food Science
Subjects:
Iron deficiency
Liver injury
Alcohol
DEN
Ferroptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2665927122002040

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http://www.sciencedirect.com/science/article/pii/S2665927122002040

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