Traumatic brain ischemia during neuro intensive care: myth rather than fact
In non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic parameters have been misinterpreted, or when cere...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
2001-09-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400001&tlng=en |
| _version_ | 1819282403044098048 |
|---|---|
| author | Julio Cruz |
| author_facet | Julio Cruz |
| author_sort | Julio Cruz |
| collection | DOAJ |
| description | In non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic parameters have been misinterpreted, or when cerebral blood flow (CBF) alone has been addressed in a biased fashion, without mandatory metabolic data. Indeed, comprehensive and unbiased studies focusing on global cerebral metabolic activity have invariably revealed a condition of normal coupling between reduced CBF and oxygen consumption in the early postinjury hours, which is then followed by a prolonged, sustained pattern of relative cerebral hyperperfusion (the opposite of ischemia). Accordingly, traumatic brain ischemia during intensive care represents myth rather than fact. |
| first_indexed | 2024-12-24T01:15:02Z |
| format | Article |
| id | doaj.art-488098d1fdd54610afaddecb59ac8dbc |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-24T01:15:02Z |
| publishDate | 2001-09-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-488098d1fdd54610afaddecb59ac8dbc2022-12-21T17:22:47ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272001-09-01593A47948210.1590/S0004-282X2001000400001Traumatic brain ischemia during neuro intensive care: myth rather than factJulio Cruz0Comprehensive International Center for NeuroemergenciesIn non-missile severe acute brain trauma, brain ischemia was a frequent finding in cadavers. Studies during neuro intensive care, however, have failed to disclose brain ischemia under most circumstances, except when cerebral hemodynamic and metabolic parameters have been misinterpreted, or when cerebral blood flow (CBF) alone has been addressed in a biased fashion, without mandatory metabolic data. Indeed, comprehensive and unbiased studies focusing on global cerebral metabolic activity have invariably revealed a condition of normal coupling between reduced CBF and oxygen consumption in the early postinjury hours, which is then followed by a prolonged, sustained pattern of relative cerebral hyperperfusion (the opposite of ischemia). Accordingly, traumatic brain ischemia during intensive care represents myth rather than fact.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400001&tlng=enhead injurycerebral metabolismcerebral blood flowbrain ischemia |
| spellingShingle | Julio Cruz Traumatic brain ischemia during neuro intensive care: myth rather than fact Arquivos de Neuro-Psiquiatria head injury cerebral metabolism cerebral blood flow brain ischemia |
| title | Traumatic brain ischemia during neuro intensive care: myth rather than fact |
| title_full | Traumatic brain ischemia during neuro intensive care: myth rather than fact |
| title_fullStr | Traumatic brain ischemia during neuro intensive care: myth rather than fact |
| title_full_unstemmed | Traumatic brain ischemia during neuro intensive care: myth rather than fact |
| title_short | Traumatic brain ischemia during neuro intensive care: myth rather than fact |
| title_sort | traumatic brain ischemia during neuro intensive care myth rather than fact |
| topic | head injury cerebral metabolism cerebral blood flow brain ischemia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000400001&tlng=en |
| work_keys_str_mv | AT juliocruz traumaticbrainischemiaduringneurointensivecaremythratherthanfact |