New 2-aryl-7,8-dimethoxy-3,4-dihydroisoquinolin-2-ium salts as potential antifungal agents: synthesis, bioactivity and structure-activity relationships

New 2-aryl-7,8-dimethoxy-3,4-dihydroisoquinolin-2-ium salts as potential antifungal agents: synthesis, bioactivity and structure-activity relationships

Abstract The title compounds can be considered as simple analogues of quaternary benzo[c]phenanthridine alkaloids (QBAs). In order to develop potent QBA-like antifungal agents, as our continuing study, a series of new title compounds were synthesized and evaluated for bioactivity against five plant...

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Bibliographic Details
Main Authors:	Lifei Zhu, Bohang Zhou, Bingyu Zhang, Mingxuan Xu, Huiling Geng, Le Zhou
Format:	Article
Language:	English
Published:	Nature Portfolio 2017-08-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-07303-8

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