Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference
Recall-by-Genotype (RbG) is an approach to recall participants from genetic studies based on their specific genotype for further, more extensive phenotyping. Here, the authors discuss examples of RbG as well as practical and ethical considerations and provide an online tool to aid in designing RbG s...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2018-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-03109-y |
| _version_ | 1818978170748010496 |
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| author | Laura J. Corbin Vanessa Y. Tan David A. Hughes Kaitlin H. Wade Dirk S. Paul Katherine E. Tansey Frances Butcher Frank Dudbridge Joanna M. Howson Momodou W. Jallow Catherine John Nathalie Kingston Cecilia M. Lindgren Michael O’Donavan Stephen O’Rahilly Michael J. Owen Colin N. A. Palmer Ewan R. Pearson Robert A. Scott David A. van Heel John Whittaker Tim Frayling Martin D. Tobin Louise V. Wain George Davey Smith David M. Evans Fredrik Karpe Mark I. McCarthy John Danesh Paul W. Franks Nicholas J. Timpson |
| author_facet | Laura J. Corbin Vanessa Y. Tan David A. Hughes Kaitlin H. Wade Dirk S. Paul Katherine E. Tansey Frances Butcher Frank Dudbridge Joanna M. Howson Momodou W. Jallow Catherine John Nathalie Kingston Cecilia M. Lindgren Michael O’Donavan Stephen O’Rahilly Michael J. Owen Colin N. A. Palmer Ewan R. Pearson Robert A. Scott David A. van Heel John Whittaker Tim Frayling Martin D. Tobin Louise V. Wain George Davey Smith David M. Evans Fredrik Karpe Mark I. McCarthy John Danesh Paul W. Franks Nicholas J. Timpson |
| author_sort | Laura J. Corbin |
| collection | DOAJ |
| description | Recall-by-Genotype (RbG) is an approach to recall participants from genetic studies based on their specific genotype for further, more extensive phenotyping. Here, the authors discuss examples of RbG as well as practical and ethical considerations and provide an online tool to aid in designing RbG studies. |
| first_indexed | 2024-12-20T16:39:23Z |
| format | Article |
| id | doaj.art-4889e7ce60af487a8fa26fd2a38318e8 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:39:23Z |
| publishDate | 2018-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-4889e7ce60af487a8fa26fd2a38318e82022-12-21T19:33:03ZengNature PortfolioNature Communications2041-17232018-02-019111110.1038/s41467-018-03109-yFormalising recall by genotype as an efficient approach to detailed phenotyping and causal inferenceLaura J. Corbin0Vanessa Y. Tan1David A. Hughes2Kaitlin H. Wade3Dirk S. Paul4Katherine E. Tansey5Frances Butcher6Frank Dudbridge7Joanna M. Howson8Momodou W. Jallow9Catherine John10Nathalie Kingston11Cecilia M. Lindgren12Michael O’Donavan13Stephen O’Rahilly14Michael J. Owen15Colin N. A. Palmer16Ewan R. Pearson17Robert A. Scott18David A. van Heel19John Whittaker20Tim Frayling21Martin D. Tobin22Louise V. Wain23George Davey Smith24David M. Evans25Fredrik Karpe26Mark I. McCarthy27John Danesh28Paul W. Franks29Nicholas J. Timpson30MRC Integrative Epidemiology Unit at University of BristolMRC Integrative Epidemiology Unit at University of BristolMRC Integrative Epidemiology Unit at University of BristolMRC Integrative Epidemiology Unit at University of BristolMRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of CambridgeCore Bioinformatics and Statistics Team, College of Biomedical & Life Sciences, Cardiff UniversityOxford School of Public Health, University of OxfordDepartment of Health Sciences, University of LeicesterMRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of CambridgeDepartment of Epidemiology and Population Health, London School of Hygiene and Tropical MedicineDepartment of Health Sciences, University of LeicesterNational Institute for Health Research (NIHR) BioResource for Translational Research in Common and Rare Diseases & NIHR BioResource Centre Cambridge, University of CambridgeBig Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of OxfordMRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff UniversityMetabolic Research Laboratories, Institute of Metabolic Science, University of CambridgeMRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff UniversityMedical Research Institute, University of Dundee, Ninewells Hospital and Medical SchoolMedical Research Institute, University of Dundee, Ninewells Hospital and Medical SchoolQuantitative Sciences, GlaxoSmithKlineBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of LondonDepartment of Epidemiology and Population Health, London School of Hygiene and Tropical MedicineGenetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter HospitalDepartment of Health Sciences, University of LeicesterDepartment of Health Sciences, University of LeicesterMRC Integrative Epidemiology Unit at University of BristolMRC Integrative Epidemiology Unit at University of BristolOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of OxfordWellcome Trust Centre for Human Genetics, University of OxfordMRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of CambridgeOxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of OxfordMRC Integrative Epidemiology Unit at University of BristolRecall-by-Genotype (RbG) is an approach to recall participants from genetic studies based on their specific genotype for further, more extensive phenotyping. Here, the authors discuss examples of RbG as well as practical and ethical considerations and provide an online tool to aid in designing RbG studies.https://doi.org/10.1038/s41467-018-03109-y |
| spellingShingle | Laura J. Corbin Vanessa Y. Tan David A. Hughes Kaitlin H. Wade Dirk S. Paul Katherine E. Tansey Frances Butcher Frank Dudbridge Joanna M. Howson Momodou W. Jallow Catherine John Nathalie Kingston Cecilia M. Lindgren Michael O’Donavan Stephen O’Rahilly Michael J. Owen Colin N. A. Palmer Ewan R. Pearson Robert A. Scott David A. van Heel John Whittaker Tim Frayling Martin D. Tobin Louise V. Wain George Davey Smith David M. Evans Fredrik Karpe Mark I. McCarthy John Danesh Paul W. Franks Nicholas J. Timpson Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference Nature Communications |
| title | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| title_full | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| title_fullStr | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| title_full_unstemmed | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| title_short | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| title_sort | formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
| url | https://doi.org/10.1038/s41467-018-03109-y |
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