Synthesis and biological applications of some novel 8-Hydroxyquinoline urea and thiourea derivatives

Synthesis and biological applications of some novel 8-Hydroxyquinoline urea and thiourea derivatives

A number of novel urea and thiourea derivatives of 8-hydroxyquinoline have been designed, synthesized and evaluated for their anticancer activities. The structures of the new compounds were established by spectroscopic techniques, 1H NMR, 13C NMR, and mass spectrometry. The in vitro cytotoxicity aga...

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Bibliographic Details
Main Authors: Mohammad A. Khasawneh, Ayesha AlKaabi, Abdelouahid Samadi, Priya Antony, Ranjit Vijayan, Lamya Ahmed Al-Keridis, Haythem A. Saadeh, Nael Abutaha
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Arabian Journal of Chemistry
Subjects:
8-Hydroxyquinoline
Urea
Thiourea
Piperazine
Anticancer
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535222002210

Internet

http://www.sciencedirect.com/science/article/pii/S1878535222002210

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