Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients
ObjectivesThe aim of this study was to assess the potential of electrodermal activity (EDA) as a diagnostic tool for preoperative evaluation in hyperhidrosis patients. EDA levels and patterns in different skin areas were investigated before and after endoscopic thoracic sympathicotomy (ETS) and was...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1358357/full |
| _version_ | 1827321093062393856 |
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| author | Ai Van Thuy Ho Ai Van Thuy Ho Eirik Øvensen Didrik Lilja Karin Toska Karin Toska Odd Grenager Knut Kristiansen Jarlis Wesche Jarlis Wesche |
| author_facet | Ai Van Thuy Ho Ai Van Thuy Ho Eirik Øvensen Didrik Lilja Karin Toska Karin Toska Odd Grenager Knut Kristiansen Jarlis Wesche Jarlis Wesche |
| author_sort | Ai Van Thuy Ho |
| collection | DOAJ |
| description | ObjectivesThe aim of this study was to assess the potential of electrodermal activity (EDA) as a diagnostic tool for preoperative evaluation in hyperhidrosis patients. EDA levels and patterns in different skin areas were investigated before and after endoscopic thoracic sympathicotomy (ETS) and was compared to healthy subjects.MethodsThirty-seven patients underwent two days of measurements before and after the operation. Twenty-five (67.5%) of the patients also had a third measurement after six months. Non-invasive EDA measurements, involving skin conductance, were sampled from five different skin areas while patients were at rest in supine and sitting positions or when subjected to stimuli such as deep inspirations, mental challenge, and exposure to a sudden loud sound.ResultsPrior to the operation, hyperhidrosis patients showed higher spontaneous palm EDA variations at rest and stronger responses to stimuli compared to healthy subjects. Patients with facial blushing/hyperhidrosis or combined facial/palmar hyperhidrosis showed minimal spontaneous activity or responses, particularly during mental challenge and sound stimulus. Notably, palm EDA response was abolished shortly following sympathicotomy, although a minor response was observed after six months. Minimal EDA responses were also observed in the back and abdomen postoperatively.ConclusionHyperhidrosis patients showed stronger EDA response to stimuli compared to healthy subjects. Sympathicotomy resulted in the complete elimination of palm EDA responses, gradually returning to a limited extent after six months. These findings suggest that EDA recordings could be utilized in preoperative assessment of hyperhidrosis patients. |
| first_indexed | 2024-04-25T01:00:23Z |
| format | Article |
| id | doaj.art-488ab2c177464598b89eaa7d1f39376b |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-25T01:00:23Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-488ab2c177464598b89eaa7d1f39376b2024-03-11T04:58:43ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2024-03-011110.3389/fsurg.2024.13583571358357Changes in electrodermal activity following sympathicotomy in hyperhidrosis patientsAi Van Thuy Ho0Ai Van Thuy Ho1Eirik Øvensen2Didrik Lilja3Karin Toska4Karin Toska5Odd Grenager6Knut Kristiansen7Jarlis Wesche8Jarlis Wesche9The Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Thoracic and Vascular Surgery, Akershus University Hospital, Lørenskog, NorwayDepartment of Thoracic and Vascular Surgery, Akershus University Hospital, Lørenskog, NorwayThe Intervention Centre, Oslo University Hospital, Oslo, NorwayThe Faculty of Medicine, Institute of Basic Medical Sciences, University of Oslo, Oslo, NorwayDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, NorwayDepartment of Thoracic and Vascular Surgery, Akershus University Hospital, Lørenskog, NorwayDepartment of Thoracic and Vascular Surgery, Akershus University Hospital, Lørenskog, NorwayThe Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, NorwayDepartment of Thoracic and Vascular Surgery, Akershus University Hospital, Lørenskog, NorwayObjectivesThe aim of this study was to assess the potential of electrodermal activity (EDA) as a diagnostic tool for preoperative evaluation in hyperhidrosis patients. EDA levels and patterns in different skin areas were investigated before and after endoscopic thoracic sympathicotomy (ETS) and was compared to healthy subjects.MethodsThirty-seven patients underwent two days of measurements before and after the operation. Twenty-five (67.5%) of the patients also had a third measurement after six months. Non-invasive EDA measurements, involving skin conductance, were sampled from five different skin areas while patients were at rest in supine and sitting positions or when subjected to stimuli such as deep inspirations, mental challenge, and exposure to a sudden loud sound.ResultsPrior to the operation, hyperhidrosis patients showed higher spontaneous palm EDA variations at rest and stronger responses to stimuli compared to healthy subjects. Patients with facial blushing/hyperhidrosis or combined facial/palmar hyperhidrosis showed minimal spontaneous activity or responses, particularly during mental challenge and sound stimulus. Notably, palm EDA response was abolished shortly following sympathicotomy, although a minor response was observed after six months. Minimal EDA responses were also observed in the back and abdomen postoperatively.ConclusionHyperhidrosis patients showed stronger EDA response to stimuli compared to healthy subjects. Sympathicotomy resulted in the complete elimination of palm EDA responses, gradually returning to a limited extent after six months. These findings suggest that EDA recordings could be utilized in preoperative assessment of hyperhidrosis patients.https://www.frontiersin.org/articles/10.3389/fsurg.2024.1358357/fullhyperhidrosispalmar hyperhidrosisfacial blushingfacial hyperhidrosiselectrodermal activityendoscopic thoracic sympathicotomy |
| spellingShingle | Ai Van Thuy Ho Ai Van Thuy Ho Eirik Øvensen Didrik Lilja Karin Toska Karin Toska Odd Grenager Knut Kristiansen Jarlis Wesche Jarlis Wesche Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients Frontiers in Surgery hyperhidrosis palmar hyperhidrosis facial blushing facial hyperhidrosis electrodermal activity endoscopic thoracic sympathicotomy |
| title | Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| title_full | Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| title_fullStr | Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| title_full_unstemmed | Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| title_short | Changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| title_sort | changes in electrodermal activity following sympathicotomy in hyperhidrosis patients |
| topic | hyperhidrosis palmar hyperhidrosis facial blushing facial hyperhidrosis electrodermal activity endoscopic thoracic sympathicotomy |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1358357/full |
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