Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting
Abstract Postoperative cognitive dysfunction is a common complication following cardiac surgery. The incidence of cognitive dysfunction is more pronounced in patients receiving a cardiac operation than in those undergoing a non-cardiac operation. Clinical observations demonstrated that pulsatile flo...
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Cirurgia Cardiovascular
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| Series: | Brazilian Journal of Cardiovascular Surgery |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000100076&lng=en&tlng=en |
| _version_ | 1818231998903222272 |
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| author | Shi-Min Yuan Hong Lin |
| author_facet | Shi-Min Yuan Hong Lin |
| author_sort | Shi-Min Yuan |
| collection | DOAJ |
| description | Abstract Postoperative cognitive dysfunction is a common complication following cardiac surgery. The incidence of cognitive dysfunction is more pronounced in patients receiving a cardiac operation than in those undergoing a non-cardiac operation. Clinical observations demonstrated that pulsatile flow was superior to nonpulsatile flow, and membrane oxygenator was superior to bubble oxygenator in terms of postoperative cognitive status. Nevertheless, cognitive assessments in patients receiving an on-pump and off-pump coronary artery bypass surgery have yielded inconsistent results. The exact mechanisms of postoperative cognitive dysfunction following coronary artery bypass grafting remain uncertain. The dual effects, neuroprotective and neurotoxic, of anesthetics should be thoroughly investigated. The diagnosis should be based on a comprehensive cognitive evaluation with neuropsychiatric tests, cerebral biomarker inspections, and electroencephalographic examination. The management strategies for cognitive dysfunction can be preventive or therapeutic. The preventive strategies of modifying surgical facilities and techniques can be effective for preventing the development of postoperative cognitive dysfunction. Investigational therapies may offer novel strategies of treatments. Anesthetic preconditioning might be helpful for the improvement of this dysfunction. |
| first_indexed | 2024-12-12T10:59:18Z |
| format | Article |
| id | doaj.art-48907685722d4b3d84dc22d42a76199a |
| institution | Directory Open Access Journal |
| issn | 1678-9741 |
| language | English |
| last_indexed | 2024-12-12T10:59:18Z |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| record_format | Article |
| series | Brazilian Journal of Cardiovascular Surgery |
| spelling | doaj.art-48907685722d4b3d84dc22d42a76199a2022-12-22T00:26:35ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-9741341768410.21470/1678-9741-2018-0165S0102-76382019000100076Postoperative Cognitive Dysfunction after Coronary Artery Bypass GraftingShi-Min YuanHong LinAbstract Postoperative cognitive dysfunction is a common complication following cardiac surgery. The incidence of cognitive dysfunction is more pronounced in patients receiving a cardiac operation than in those undergoing a non-cardiac operation. Clinical observations demonstrated that pulsatile flow was superior to nonpulsatile flow, and membrane oxygenator was superior to bubble oxygenator in terms of postoperative cognitive status. Nevertheless, cognitive assessments in patients receiving an on-pump and off-pump coronary artery bypass surgery have yielded inconsistent results. The exact mechanisms of postoperative cognitive dysfunction following coronary artery bypass grafting remain uncertain. The dual effects, neuroprotective and neurotoxic, of anesthetics should be thoroughly investigated. The diagnosis should be based on a comprehensive cognitive evaluation with neuropsychiatric tests, cerebral biomarker inspections, and electroencephalographic examination. The management strategies for cognitive dysfunction can be preventive or therapeutic. The preventive strategies of modifying surgical facilities and techniques can be effective for preventing the development of postoperative cognitive dysfunction. Investigational therapies may offer novel strategies of treatments. Anesthetic preconditioning might be helpful for the improvement of this dysfunction.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000100076&lng=en&tlng=enCognitive DysfunctionCoronary Artery BypassCoronary Artery Bypass, Off-PumpPostoperative Complications |
| spellingShingle | Shi-Min Yuan Hong Lin Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting Brazilian Journal of Cardiovascular Surgery Cognitive Dysfunction Coronary Artery Bypass Coronary Artery Bypass, Off-Pump Postoperative Complications |
| title | Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting |
| title_full | Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting |
| title_fullStr | Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting |
| title_full_unstemmed | Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting |
| title_short | Postoperative Cognitive Dysfunction after Coronary Artery Bypass Grafting |
| title_sort | postoperative cognitive dysfunction after coronary artery bypass grafting |
| topic | Cognitive Dysfunction Coronary Artery Bypass Coronary Artery Bypass, Off-Pump Postoperative Complications |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000100076&lng=en&tlng=en |
| work_keys_str_mv | AT shiminyuan postoperativecognitivedysfunctionaftercoronaryarterybypassgrafting AT honglin postoperativecognitivedysfunctionaftercoronaryarterybypassgrafting |