Genome-wide map of R-loops reveals its interplay with transcription and genome integrity during germ cell meiosis

Genome-wide map of R-loops reveals its interplay with transcription and genome integrity during germ cell meiosis

Introduction: The R-loop is a naturally formed three-strand nucleic acid structure that recently has been reported to participate in multiple biological processes and helped answer some previously unexplained scientific questions. Meiosis process involves multiple chromatin-related events such as DN...

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Bibliographic Details
Main Authors: Yu Jiang, Fei Huang, Lu Chen, Jia-Hui Gu, Yun-Wen Wu, Meng-Yan Jia, Zhen Lin, Yong Zhou, Yan-Chu Li, Chao Yu, Ming-Han Tong, Li Shen, Heng-Yu Fan, Qian-Qian Sha
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Advanced Research
Subjects:
R-loop
Meiosis
Spermatogenesis
Genome stability
Homologous recombination
DNA repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222002454

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