On the main stages of the history of intra-articular therapy
In this review the main stages in the history of intra-articular therapy of the rheumatic diseases are summarized. The first approach to such a local treatment has been likely performed in 1792 by the French physician Jean Gay, who injected in a swelling knee the “eau du Goulard” (Goulard’s water),...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2011-09-01
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| Series: | Reumatismo |
| Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/336 |
| _version_ | 1811234216818507776 |
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| author | L. Punzi G. Pasero P. Marson G. Zanchin |
| author_facet | L. Punzi G. Pasero P. Marson G. Zanchin |
| author_sort | L. Punzi |
| collection | DOAJ |
| description | In this review the main stages in the history of intra-articular therapy of the rheumatic diseases are summarized. The first approach to such a local treatment has been likely performed in 1792 by the French physician Jean Gay, who injected in a swelling knee the “eau du Goulard” (Goulard’s water), namely a mixture based on lead compounds. In the XIX century iodine derivatives have been mainly applied as an intra-articular treatment. In the XX century, before the wide use of intra-articular corticosteroids, chiefly due to the Joseph Lee Hollander’s experiences, a variety of drugs has been employed, including cytostatics and sclerosing substances. A further important stage has been synoviorthesis, by using specific radionuclides, that would actually represent an anti-synovial treatment. In the last years a spread use of intra-articular hyaluronic acid, particularly in osteoarthritis, has been recorded, with the aim to warrant articular viscosupplementation. Future of intra-articular treatment should be represented by the biological drugs, i.e., anti-TNF, but it is still untimely to define the exact role of such a local treatment of arthritis. |
| first_indexed | 2024-04-12T11:32:59Z |
| format | Article |
| id | doaj.art-48978e772fe043d4b0b58f15d7a71d74 |
| institution | Directory Open Access Journal |
| issn | 0048-7449 2240-2683 |
| language | English |
| last_indexed | 2024-04-12T11:32:59Z |
| publishDate | 2011-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Reumatismo |
| spelling | doaj.art-48978e772fe043d4b0b58f15d7a71d742022-12-22T03:34:55ZengPAGEPress PublicationsReumatismo0048-74492240-26832011-09-0159326226810.4081/reumatismo.2007.262On the main stages of the history of intra-articular therapyL. PunziG. PaseroP. MarsonG. ZanchinIn this review the main stages in the history of intra-articular therapy of the rheumatic diseases are summarized. The first approach to such a local treatment has been likely performed in 1792 by the French physician Jean Gay, who injected in a swelling knee the “eau du Goulard” (Goulard’s water), namely a mixture based on lead compounds. In the XIX century iodine derivatives have been mainly applied as an intra-articular treatment. In the XX century, before the wide use of intra-articular corticosteroids, chiefly due to the Joseph Lee Hollander’s experiences, a variety of drugs has been employed, including cytostatics and sclerosing substances. A further important stage has been synoviorthesis, by using specific radionuclides, that would actually represent an anti-synovial treatment. In the last years a spread use of intra-articular hyaluronic acid, particularly in osteoarthritis, has been recorded, with the aim to warrant articular viscosupplementation. Future of intra-articular treatment should be represented by the biological drugs, i.e., anti-TNF, but it is still untimely to define the exact role of such a local treatment of arthritis.http://www.reumatismo.org/index.php/reuma/article/view/336 |
| spellingShingle | L. Punzi G. Pasero P. Marson G. Zanchin On the main stages of the history of intra-articular therapy Reumatismo |
| title | On the main stages of the history of intra-articular therapy |
| title_full | On the main stages of the history of intra-articular therapy |
| title_fullStr | On the main stages of the history of intra-articular therapy |
| title_full_unstemmed | On the main stages of the history of intra-articular therapy |
| title_short | On the main stages of the history of intra-articular therapy |
| title_sort | on the main stages of the history of intra articular therapy |
| url | http://www.reumatismo.org/index.php/reuma/article/view/336 |
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