Induction of IFNα or IL-12 depends on differentiation of THP-1 cells in dengue infections without and with antibody enhancement

Induction of IFNα or IL-12 depends on differentiation of THP-1 cells in dengue infections without and with antibody enhancement

<p>Abstract</p> <p>Background</p> <p>Appropriate induction of the early Th1 cytokine IL-12 is a critical defense directed against viral infection. We have previously shown that different viruses elicited either IL-12 or IFNα dependent Th1 reactions. Using dengue-2 virus...

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Bibliographic Details
Main Authors: Chen Rong-Fu, Wang Lin, Cheng Jiin-Tsuey, Yang Kuender D
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Infectious Diseases
Subjects:
Monocyte
Deneritic cells
Differentiation
CD123
IFNα
IL-12
Online Access:http://www.biomedcentral.com/1471-2334/12/340

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