Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review
Background: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultim...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Biomimetics |
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| Online Access: | https://www.mdpi.com/2313-7673/7/2/74 |
| _version_ | 1827661982697783296 |
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| author | Mariana Brito Cruz Neusa Silva Joana Faria Marques António Mata Felipe Samuel Silva João Caramês |
| author_facet | Mariana Brito Cruz Neusa Silva Joana Faria Marques António Mata Felipe Samuel Silva João Caramês |
| author_sort | Mariana Brito Cruz |
| collection | DOAJ |
| description | Background: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and biological characteristics in order to determine the critical parameters to improve biological responses and the long-term effectiveness of dental implant surfaces. Data sources and methods: Web of Science, MEDLINE and Lilacs databases were searched for the last 30 years in English, Spanish and Portuguese idioms. Results: Chemical composition, wettability, roughness, and topography of dental implant surfaces have all been linked to biological regulation in cell interactions, osseointegration, bone tissue and peri-implant mucosa preservation. Conclusion: Techniques involving subtractive and additive methods, especially those involving laser treatment or embedding of bioactive nanoparticles, have demonstrated promising results. However, the literature is heterogeneous regarding study design and methodology, which limits comparisons between studies and the definition of the critical determinants of optimal cell response. |
| first_indexed | 2024-03-10T00:18:47Z |
| format | Article |
| id | doaj.art-489b3110a5944092a4cf8a75e8109306 |
| institution | Directory Open Access Journal |
| issn | 2313-7673 |
| language | English |
| last_indexed | 2024-03-10T00:18:47Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomimetics |
| spelling | doaj.art-489b3110a5944092a4cf8a75e81093062023-11-23T15:45:54ZengMDPI AGBiomimetics2313-76732022-06-01727410.3390/biomimetics7020074Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise ReviewMariana Brito Cruz0Neusa Silva1Joana Faria Marques2António Mata3Felipe Samuel Silva4João Caramês5Universidade de Lisboa, Faculdade de Medicina Dentária, Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Rua Professora Teresa Ambrósio, 1600-277 Lisboa, PortugalUniversidade de Lisboa, Faculdade de Medicina Dentária, Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), LIBPhys-FTC UID/FIS/04559/2013, Rua Professora Teresa Ambrósio, 1600-277 Lisboa, PortugalUniversidade de Lisboa, Faculdade de Medicina Dentária, Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Rua Professora Teresa Ambrósio, 1600-277 Lisboa, PortugalUniversidade de Lisboa, Faculdade de Medicina Dentária, Unidade de Investigação em Ciências Orais e Biomédicas (UICOB), Rua Professora Teresa Ambrósio, 1600-277 Lisboa, PortugalCenter for Microelectromechanical Systems (CMEMS), Department of Mechanical Engineering, University of Minho, 4800-058 Guimarães, PortugalBone Physiology Research Group, Faculdade de Medicina Dentária, Universidade de Lisboa, Rua Professora Teresa Ambrósio, 1600-277 Lisboa, PortugalBackground: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and biological characteristics in order to determine the critical parameters to improve biological responses and the long-term effectiveness of dental implant surfaces. Data sources and methods: Web of Science, MEDLINE and Lilacs databases were searched for the last 30 years in English, Spanish and Portuguese idioms. Results: Chemical composition, wettability, roughness, and topography of dental implant surfaces have all been linked to biological regulation in cell interactions, osseointegration, bone tissue and peri-implant mucosa preservation. Conclusion: Techniques involving subtractive and additive methods, especially those involving laser treatment or embedding of bioactive nanoparticles, have demonstrated promising results. However, the literature is heterogeneous regarding study design and methodology, which limits comparisons between studies and the definition of the critical determinants of optimal cell response.https://www.mdpi.com/2313-7673/7/2/74implant surfaceosseointegrationdentistryoral surgeryoral rehabilitationbiomimetic |
| spellingShingle | Mariana Brito Cruz Neusa Silva Joana Faria Marques António Mata Felipe Samuel Silva João Caramês Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review Biomimetics implant surface osseointegration dentistry oral surgery oral rehabilitation biomimetic |
| title | Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review |
| title_full | Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review |
| title_fullStr | Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review |
| title_full_unstemmed | Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review |
| title_short | Biomimetic Implant Surfaces and Their Role in Biological Integration—A Concise Review |
| title_sort | biomimetic implant surfaces and their role in biological integration a concise review |
| topic | implant surface osseointegration dentistry oral surgery oral rehabilitation biomimetic |
| url | https://www.mdpi.com/2313-7673/7/2/74 |
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