Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom
We evaluate the combined usage of two systems, the Integral Quality Monitor (IQM) transmission detector and SoftDiso software, for in vivo dose monitoring by simultaneous detection of delivery and patient setup errors in whole breast irradiation. An Alderson RANDO phantom was adapted with silicon br...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/10/21/7611 |
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| author | Chiara Arilli Yannik Wandael Chiara Galeotti Livia Marrazzo Silvia Calusi Mattia Grusio Isacco Desideri Franco Fusi Angelo Piermattei Stefania Pallotta Cinzia Talamonti |
| author_facet | Chiara Arilli Yannik Wandael Chiara Galeotti Livia Marrazzo Silvia Calusi Mattia Grusio Isacco Desideri Franco Fusi Angelo Piermattei Stefania Pallotta Cinzia Talamonti |
| author_sort | Chiara Arilli |
| collection | DOAJ |
| description | We evaluate the combined usage of two systems, the Integral Quality Monitor (IQM) transmission detector and SoftDiso software, for in vivo dose monitoring by simultaneous detection of delivery and patient setup errors in whole breast irradiation. An Alderson RANDO phantom was adapted with silicon breast prostheses to mimic the female anatomy. Plans with simulated delivery errors were created from a reference left breast plan, and patient setup errors were simulated by moving the phantom. Deviations from reference values recorded by both monitoring systems were measured for all plans and phantom positions. A 2D global gamma analysis was performed in SoftDiso for all phantom displacements. Both IQM signals and SoftDiso R-values are sensitive to small MU variations. However, only IQM is sensitive to jaw position variations. Conversely, IQM is unable to detect patient positioning errors, and the R-value has good sensitivity to phantom displacements. A gamma comparison analysis allows one to determine alert thresholds to detect phantom shifts or relatively large rotations. The combined use of the IQM and SoftDiso allows for fast identification of both delivery and setup errors and substantially reduces the impact of error identification and correction on the treatment workflow. |
| first_indexed | 2024-03-10T15:15:42Z |
| format | Article |
| id | doaj.art-489b8240a50b4b8e93aa9abb8136cbfd |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T15:15:42Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-489b8240a50b4b8e93aa9abb8136cbfd2023-11-20T18:55:44ZengMDPI AGApplied Sciences2076-34172020-10-011021761110.3390/app10217611Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female PhantomChiara Arilli0Yannik Wandael1Chiara Galeotti2Livia Marrazzo3Silvia Calusi4Mattia Grusio5Isacco Desideri6Franco Fusi7Angelo Piermattei8Stefania Pallotta9Cinzia Talamonti10AOU Careggi, Medical Physics Unit, 50134 Florence, ItalyAOU Careggi, Radiotherapy Unit, 50134 Florence, ItalyAOU Careggi, Radiotherapy Unit, 50134 Florence, ItalyAOU Careggi, Medical Physics Unit, 50134 Florence, ItalyDepartment of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, 50134 Florence, ItalyUOC Fisica Sanitaria, Fondazione Policlinico Universitario Agostino Gemelli, 00168 Rome, ItalyDepartment of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, 50134 Florence, ItalyDepartment of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, 50134 Florence, ItalyUOC Fisica Sanitaria, Fondazione Policlinico Universitario Agostino Gemelli, 00168 Rome, ItalyAOU Careggi, Medical Physics Unit, 50134 Florence, ItalyAOU Careggi, Medical Physics Unit, 50134 Florence, ItalyWe evaluate the combined usage of two systems, the Integral Quality Monitor (IQM) transmission detector and SoftDiso software, for in vivo dose monitoring by simultaneous detection of delivery and patient setup errors in whole breast irradiation. An Alderson RANDO phantom was adapted with silicon breast prostheses to mimic the female anatomy. Plans with simulated delivery errors were created from a reference left breast plan, and patient setup errors were simulated by moving the phantom. Deviations from reference values recorded by both monitoring systems were measured for all plans and phantom positions. A 2D global gamma analysis was performed in SoftDiso for all phantom displacements. Both IQM signals and SoftDiso R-values are sensitive to small MU variations. However, only IQM is sensitive to jaw position variations. Conversely, IQM is unable to detect patient positioning errors, and the R-value has good sensitivity to phantom displacements. A gamma comparison analysis allows one to determine alert thresholds to detect phantom shifts or relatively large rotations. The combined use of the IQM and SoftDiso allows for fast identification of both delivery and setup errors and substantially reduces the impact of error identification and correction on the treatment workflow.https://www.mdpi.com/2076-3417/10/21/7611quality assurancein vivo dosimetrytransmission radiation detectorswhole breast irradiation |
| spellingShingle | Chiara Arilli Yannik Wandael Chiara Galeotti Livia Marrazzo Silvia Calusi Mattia Grusio Isacco Desideri Franco Fusi Angelo Piermattei Stefania Pallotta Cinzia Talamonti Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom Applied Sciences quality assurance in vivo dosimetry transmission radiation detectors whole breast irradiation |
| title | Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom |
| title_full | Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom |
| title_fullStr | Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom |
| title_full_unstemmed | Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom |
| title_short | Combined Use of a Transmission Detector and an EPID-Based In Vivo Dose Monitoring System in External Beam Whole Breast Irradiation: A Study with an Anthropomorphic Female Phantom |
| title_sort | combined use of a transmission detector and an epid based in vivo dose monitoring system in external beam whole breast irradiation a study with an anthropomorphic female phantom |
| topic | quality assurance in vivo dosimetry transmission radiation detectors whole breast irradiation |
| url | https://www.mdpi.com/2076-3417/10/21/7611 |
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