Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients
Background: Behcet’s disease is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s dis...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2022-06-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-2957-en.html |
| _version_ | 1811225424942858240 |
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| author | Maryam Masoumi Alireza Sharifi Sepideh Rezaei Sima Rafiei Hossein Hosseinifard Saghar Khani Maryam Doustmehraban Mona Rajabi Zahra Beiramy Chomalou Parisa Soori Akbar Javan Biparva Afsaneh Dehnad Fatemeh Pashazadeh kan Ahmad Ghashghaee |
| author_facet | Maryam Masoumi Alireza Sharifi Sepideh Rezaei Sima Rafiei Hossein Hosseinifard Saghar Khani Maryam Doustmehraban Mona Rajabi Zahra Beiramy Chomalou Parisa Soori Akbar Javan Biparva Afsaneh Dehnad Fatemeh Pashazadeh kan Ahmad Ghashghaee |
| author_sort | Maryam Masoumi |
| collection | DOAJ |
| description | Background: Behcet’s disease is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s disease.
Methods: A total of 13 articles were extracted from four main databases including PubMed, EMBASE, Scopus, and Web of Science from the onset of 2000 to January 2021. All studies published in English with the purpose of examining quality of life (QOL) among patients with BD or investigating its main determinants were included.
Results: Totally, 1137 BD patients participated in 13 studies. Based on random effect analysis, the total score of physical health-related QOL was 46.7 (95% CI=41.26 to 52.13) and the total score of mental health-related QOL was 49.01 (95% CI=43.83 to 54.18) representing a moderate level of QOL among BD patients. Furthermore, weighted effect size analyses showed a significant correlation between QOL and variables such as patients’ age, gender, disease duration and depression (pvalue: 0.00).
Conclusion: As the symptoms of BD worsen over time, patients confront with more severe body pain, mobility restrictions, and difficulties in chewing, eating, speaking and swallowing which negatively affect social interactions of patients and reduce their QOL. Furthermore, depression was proved to act as a deteriorating factor for HRQOL among BD patients. Thus, patients need to be psychologically supported by a specialized team and be informed during the course of treatment to gain useful information about the disease, treatment approaches and coping strategies. |
| first_indexed | 2024-04-12T09:07:02Z |
| format | Article |
| id | doaj.art-489bcf36746b4a2493f657e928fdd8e6 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-04-12T09:07:02Z |
| publishDate | 2022-06-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-489bcf36746b4a2493f657e928fdd8e62022-12-22T03:39:04ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722022-06-01133447457Global systematic review and meta-analysis of health-related quality of life in Behcet’s patientsMaryam Masoumi0Alireza Sharifi1Sepideh Rezaei2Sima Rafiei3Hossein Hosseinifard4Saghar Khani5Maryam Doustmehraban6Mona Rajabi7Zahra Beiramy Chomalou8Parisa Soori9Akbar Javan Biparva10Afsaneh Dehnad11Fatemeh Pashazadeh kan12Ahmad Ghashghaee13 Clinical Research and Development Center, Qom University of Medical Sciences, Qom, Iran Clinical Research and Development Center, Qom University of Medical Sciences, Qom, Iran School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran School of Medicine, Iran University of Medical Sciences, Tehran, Iran Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran Student Research Committee, School of Health Management and Medical Informatics, Iranian Center of Excellence in Health Management, Tabriz University of Medical Sciences, Tabriz, Iran School of Health Management and Information Sciences, Center for Educational Research in Medical Sciences (CERMS), Iran University of Medical Sciences, Tehran, Iran Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran Background: Behcet’s disease is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s disease. Methods: A total of 13 articles were extracted from four main databases including PubMed, EMBASE, Scopus, and Web of Science from the onset of 2000 to January 2021. All studies published in English with the purpose of examining quality of life (QOL) among patients with BD or investigating its main determinants were included. Results: Totally, 1137 BD patients participated in 13 studies. Based on random effect analysis, the total score of physical health-related QOL was 46.7 (95% CI=41.26 to 52.13) and the total score of mental health-related QOL was 49.01 (95% CI=43.83 to 54.18) representing a moderate level of QOL among BD patients. Furthermore, weighted effect size analyses showed a significant correlation between QOL and variables such as patients’ age, gender, disease duration and depression (pvalue: 0.00). Conclusion: As the symptoms of BD worsen over time, patients confront with more severe body pain, mobility restrictions, and difficulties in chewing, eating, speaking and swallowing which negatively affect social interactions of patients and reduce their QOL. Furthermore, depression was proved to act as a deteriorating factor for HRQOL among BD patients. Thus, patients need to be psychologically supported by a specialized team and be informed during the course of treatment to gain useful information about the disease, treatment approaches and coping strategies.http://caspjim.com/article-1-2957-en.htmlkeywords: globalhealth-related quality of lifebehcet’s diseasesystematic review. |
| spellingShingle | Maryam Masoumi Alireza Sharifi Sepideh Rezaei Sima Rafiei Hossein Hosseinifard Saghar Khani Maryam Doustmehraban Mona Rajabi Zahra Beiramy Chomalou Parisa Soori Akbar Javan Biparva Afsaneh Dehnad Fatemeh Pashazadeh kan Ahmad Ghashghaee Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients Caspian Journal of Internal Medicine keywords: global health-related quality of life behcet’s disease systematic review. |
| title | Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients |
| title_full | Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients |
| title_fullStr | Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients |
| title_full_unstemmed | Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients |
| title_short | Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients |
| title_sort | global systematic review and meta analysis of health related quality of life in behcet s patients |
| topic | keywords: global health-related quality of life behcet’s disease systematic review. |
| url | http://caspjim.com/article-1-2957-en.html |
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