Development and validation of a 3D printed antiviral ventilator filter - a comparative study
Abstract Background The current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which form an essential part of the ventilator circuit have been affected by t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | BMC Anesthesiology |
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| Online Access: | https://doi.org/10.1186/s12871-021-01310-z |
| _version_ | 1818611237748998144 |
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| author | Ruth Shaylor Mathew Francis Esther Shaylor Solomon Dadia Barak Cohen |
| author_facet | Ruth Shaylor Mathew Francis Esther Shaylor Solomon Dadia Barak Cohen |
| author_sort | Ruth Shaylor |
| collection | DOAJ |
| description | Abstract Background The current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which form an essential part of the ventilator circuit have been affected by these issues. Three-dimensional (3D) printing may provide a solution to some of these issues. Methods We designed and tested 3D printed heat and moisture exchange (HME) and antiviral casing. For each casing we tested two different filter materials derived from a sediment water filter cartridge or 1.5-μm glass fiber filter paper. A polyurethane sponge was used for the HME. Each design was tested for circuit leak, circuit compliance, peak inspiratory pressure and casing integrity using methylene blue dye. Results We designed, produced, and tested two different types of antiviral filters with six different internal configurations. Overall, we tested 10 modified filter designs and compared them with the original commercial filter. Except for the combination of 1.5-μm filter paper and 5 mm sponge peak inspiratory pressure and circuit compliance of the filters produced were within the operating limits of the ventilator. All In addition, all filters passed the dye test. Conclusions Our filter may be of particular importance to those working in low middle-income countries unable to compete with stronger economies. Our design relies on products available outside the healthcare supply chain, much of which can be purchased in grocery stores, hardware stores, or industrial and academic institutions. We hope that these HMEs and viral filters may be beneficial to clinicians who face critical supply chain issues during the COVID-19 pandemic. |
| first_indexed | 2024-12-16T15:27:08Z |
| format | Article |
| id | doaj.art-489c06a71e184406b7974babf9ff7e81 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-12-16T15:27:08Z |
| publishDate | 2021-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-489c06a71e184406b7974babf9ff7e812022-12-21T22:26:27ZengBMCBMC Anesthesiology1471-22532021-04-012111610.1186/s12871-021-01310-zDevelopment and validation of a 3D printed antiviral ventilator filter - a comparative studyRuth Shaylor0Mathew Francis1Esther Shaylor2Solomon Dadia3Barak Cohen4Division of Anesthesia, Intensive Care, and Pain Management, Tel-Aviv Medical Center; Tel-Aviv UniversityDepartment of Food Science, University of LeedsSupply Division, United Nations Children’s FundSurgical 3D printing Laboratory, Tel-Aviv Medical CenterDivision of Anesthesia, Intensive Care, and Pain Management, Tel-Aviv Medical Center; Tel-Aviv UniversityAbstract Background The current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which form an essential part of the ventilator circuit have been affected by these issues. Three-dimensional (3D) printing may provide a solution to some of these issues. Methods We designed and tested 3D printed heat and moisture exchange (HME) and antiviral casing. For each casing we tested two different filter materials derived from a sediment water filter cartridge or 1.5-μm glass fiber filter paper. A polyurethane sponge was used for the HME. Each design was tested for circuit leak, circuit compliance, peak inspiratory pressure and casing integrity using methylene blue dye. Results We designed, produced, and tested two different types of antiviral filters with six different internal configurations. Overall, we tested 10 modified filter designs and compared them with the original commercial filter. Except for the combination of 1.5-μm filter paper and 5 mm sponge peak inspiratory pressure and circuit compliance of the filters produced were within the operating limits of the ventilator. All In addition, all filters passed the dye test. Conclusions Our filter may be of particular importance to those working in low middle-income countries unable to compete with stronger economies. Our design relies on products available outside the healthcare supply chain, much of which can be purchased in grocery stores, hardware stores, or industrial and academic institutions. We hope that these HMEs and viral filters may be beneficial to clinicians who face critical supply chain issues during the COVID-19 pandemic.https://doi.org/10.1186/s12871-021-01310-zCOVID-193D printingAnesthesiaVentilatorGlobal Health |
| spellingShingle | Ruth Shaylor Mathew Francis Esther Shaylor Solomon Dadia Barak Cohen Development and validation of a 3D printed antiviral ventilator filter - a comparative study BMC Anesthesiology COVID-19 3D printing Anesthesia Ventilator Global Health |
| title | Development and validation of a 3D printed antiviral ventilator filter - a comparative study |
| title_full | Development and validation of a 3D printed antiviral ventilator filter - a comparative study |
| title_fullStr | Development and validation of a 3D printed antiviral ventilator filter - a comparative study |
| title_full_unstemmed | Development and validation of a 3D printed antiviral ventilator filter - a comparative study |
| title_short | Development and validation of a 3D printed antiviral ventilator filter - a comparative study |
| title_sort | development and validation of a 3d printed antiviral ventilator filter a comparative study |
| topic | COVID-19 3D printing Anesthesia Ventilator Global Health |
| url | https://doi.org/10.1186/s12871-021-01310-z |
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