Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)
Fungi are widely distributed in the terrestrial environment, freshwater, and marine habitat. Only approximately 100,000 of these have been classified although there are about 5.1 million characteristic fungi all over the world. These eukaryotic microbes produce specialized metabolites and participat...
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Format: | Article |
Language: | English |
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MDPI AG
2021-11-01
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Series: | Journal of Fungi |
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Online Access: | https://www.mdpi.com/2309-608X/7/12/1026 |
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author | Quan Dai Fa-Lei Zhang Tao Feng |
author_facet | Quan Dai Fa-Lei Zhang Tao Feng |
author_sort | Quan Dai |
collection | DOAJ |
description | Fungi are widely distributed in the terrestrial environment, freshwater, and marine habitat. Only approximately 100,000 of these have been classified although there are about 5.1 million characteristic fungi all over the world. These eukaryotic microbes produce specialized metabolites and participate in a variety of ecological functions, such as quorum detection, chemical defense, allelopathy, and maintenance of symbiosis. Fungi therefore remain an important resource for the screening and discovery of biologically active natural products. Sesquiterpenoids are arguably the richest natural products from plants and micro-organisms. The rearrangement of the 15 high-ductility carbons gave rise to a large number of different skeletons. At the same time, abundant structural variations lead to a diversification of biological activity. This review examines the isolation, structural determination, bioactivities, and synthesis of sesquiterpenoids that were specially produced by fungi over the past five years (2015–2020). |
first_indexed | 2024-03-10T03:47:44Z |
format | Article |
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institution | Directory Open Access Journal |
issn | 2309-608X |
language | English |
last_indexed | 2024-03-10T03:47:44Z |
publishDate | 2021-11-01 |
publisher | MDPI AG |
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series | Journal of Fungi |
spelling | doaj.art-489c77dd747b42979bc2ad640f5e5d5e2023-11-23T09:04:47ZengMDPI AGJournal of Fungi2309-608X2021-11-01712102610.3390/jof7121026Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020)Quan Dai0Fa-Lei Zhang1Tao Feng2School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, ChinaSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, ChinaSchool of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, ChinaFungi are widely distributed in the terrestrial environment, freshwater, and marine habitat. Only approximately 100,000 of these have been classified although there are about 5.1 million characteristic fungi all over the world. These eukaryotic microbes produce specialized metabolites and participate in a variety of ecological functions, such as quorum detection, chemical defense, allelopathy, and maintenance of symbiosis. Fungi therefore remain an important resource for the screening and discovery of biologically active natural products. Sesquiterpenoids are arguably the richest natural products from plants and micro-organisms. The rearrangement of the 15 high-ductility carbons gave rise to a large number of different skeletons. At the same time, abundant structural variations lead to a diversification of biological activity. This review examines the isolation, structural determination, bioactivities, and synthesis of sesquiterpenoids that were specially produced by fungi over the past five years (2015–2020).https://www.mdpi.com/2309-608X/7/12/1026sesquiterpenoidsfungusstructuresstructural diversitybiological activitysynthesis |
spellingShingle | Quan Dai Fa-Lei Zhang Tao Feng Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) Journal of Fungi sesquiterpenoids fungus structures structural diversity biological activity synthesis |
title | Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) |
title_full | Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) |
title_fullStr | Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) |
title_full_unstemmed | Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) |
title_short | Sesquiterpenoids Specially Produced by Fungi: Structures, Biological Activities, Chemical and Biosynthesis (2015–2020) |
title_sort | sesquiterpenoids specially produced by fungi structures biological activities chemical and biosynthesis 2015 2020 |
topic | sesquiterpenoids fungus structures structural diversity biological activity synthesis |
url | https://www.mdpi.com/2309-608X/7/12/1026 |
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