Ebolavirus and Haemorrhagic Syndrome
The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients. The known species with...
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| Format: | Article |
| Language: | English |
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Sultan Qaboos University
2015-05-01
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| Series: | Sultan Qaboos University Medical Journal |
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| Online Access: | http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=bac437f58fee3aaf19212126b6598f6d |
| _version_ | 1819028422216646656 |
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| author | Gerald A. Matua Dirk M. Van der Wal Rozzano C. Locsin |
| author_facet | Gerald A. Matua Dirk M. Van der Wal Rozzano C. Locsin |
| author_sort | Gerald A. Matua |
| collection | DOAJ |
| description | The Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients. The known species within the genus Ebolavirus are Bundibugyo, Sudan, Zaïre, Reston and Taï Forest. Although endemic in Africa, Ebola has caused worldwide
anxiety due to media hype and concerns about its international spread, including through bioterrorism. The high fatality rate is attributed to unavailability of a standard treatment regimen or vaccine. The disease is frightening since it is characterised by rapid immune suppression and systemic inflammatory response, causing multi-organ and system failure, shock and often death. Currently, disease management is largely supportive, with containment efforts geared towards mitigating the spread of the virus. This review describes the classification, morphology,
infective process, natural ecology, transmission, epidemic patterns, diagnosis, clinical features and immunology of Ebola, including management and epidemic containment strategies. |
| first_indexed | 2024-12-21T05:58:07Z |
| format | Article |
| id | doaj.art-489e9f8947af4467975b77bc7086d2e3 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-21T05:58:07Z |
| publishDate | 2015-05-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-489e9f8947af4467975b77bc7086d2e32022-12-21T19:13:49ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282015-05-01152e171e176Ebolavirus and Haemorrhagic SyndromeGerald A. Matua0Dirk M. Van der Wal1Rozzano C. Locsin2Department of Fundamentals & Administration, College of Nursing, Sultan Qaboos University, Muscat, OmanDepartment of Health Studies, College of Human Sciences, University of South Africa, Pretoria, South AfricaChristine E. Lynn College of Nursing, Florida Atlantic University, Boca Raton, Florida, USAThe Ebola virus is a highly virulent, single-stranded ribonucleic acid virus which affects both humans and apes and has fast become one of the world’s most feared pathogens. The virus induces acute fever and death, with haemorrhagic syndrome occurring in up to 90% of patients. The known species within the genus Ebolavirus are Bundibugyo, Sudan, Zaïre, Reston and Taï Forest. Although endemic in Africa, Ebola has caused worldwide anxiety due to media hype and concerns about its international spread, including through bioterrorism. The high fatality rate is attributed to unavailability of a standard treatment regimen or vaccine. The disease is frightening since it is characterised by rapid immune suppression and systemic inflammatory response, causing multi-organ and system failure, shock and often death. Currently, disease management is largely supportive, with containment efforts geared towards mitigating the spread of the virus. This review describes the classification, morphology, infective process, natural ecology, transmission, epidemic patterns, diagnosis, clinical features and immunology of Ebola, including management and epidemic containment strategies.http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=bac437f58fee3aaf19212126b6598f6dHemorrhagic Fever EbolaEbolavirusHemorrhageFiloviridaePathogenicity FactorsVirulenceDisease Management |
| spellingShingle | Gerald A. Matua Dirk M. Van der Wal Rozzano C. Locsin Ebolavirus and Haemorrhagic Syndrome Sultan Qaboos University Medical Journal Hemorrhagic Fever Ebola Ebolavirus Hemorrhage Filoviridae Pathogenicity Factors Virulence Disease Management |
| title | Ebolavirus and Haemorrhagic Syndrome |
| title_full | Ebolavirus and Haemorrhagic Syndrome |
| title_fullStr | Ebolavirus and Haemorrhagic Syndrome |
| title_full_unstemmed | Ebolavirus and Haemorrhagic Syndrome |
| title_short | Ebolavirus and Haemorrhagic Syndrome |
| title_sort | ebolavirus and haemorrhagic syndrome |
| topic | Hemorrhagic Fever Ebola Ebolavirus Hemorrhage Filoviridae Pathogenicity Factors Virulence Disease Management |
| url | http://web.squ.edu.om/squmj/includes/tng/pub/tNG_download.asp?id=bac437f58fee3aaf19212126b6598f6d |
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