Paediatric intracranial meningiomas: eight-year experience with 32 cases
Abstract Background The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods We retrospectively reviewed a series of 32 paediatric patients with meningiomas who...
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| Format: | Article |
| Language: | English |
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BMC
2017-07-01
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| Series: | Chinese Neurosurgical Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41016-017-0085-4 |
| _version_ | 1811205159268646912 |
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| author | Ming-chao Fan Wei Fang Ke Liu Chao Wang Wen-shuai Deng Peng Sun Wan-zhong Tang |
| author_facet | Ming-chao Fan Wei Fang Ke Liu Chao Wang Wen-shuai Deng Peng Sun Wan-zhong Tang |
| author_sort | Ming-chao Fan |
| collection | DOAJ |
| description | Abstract Background The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods We retrospectively reviewed a series of 32 paediatric patients with meningiomas who received surgical resection at the Affiliated Hospital of Qingdao University between January 2002 and December 2010. Results The study group included 17 boys and 15 girls (range: 2–18 years, mean: 13.7 years). Thirteen patients were in the first decade of life and 19 patients were in the second decade. The most common symptoms were headache (33.3%) and epilepsy (25%), followed by cranial nerve dysfunction: distortion of commissure, vision disorder, acoasma and unconsciousness. The size of lesions was ranged 35–65 mm (mean 42.3 mm). Of these 32 patients, 16 were revealed WHO class I meningiomas, 5 were WHO class II, and 11 manifested WHO class III. Nine of 32 patients met the criteria that had tumor recurrence within follow-up. Conclusions Paediatric meningiomas usually have larger size, higher pathologic grade and unusual location. The influential factors for recurrence include lesion location, histological features and extent of removal. Complete tumor resection is the best choice to prevent recurrence and improve the prognosis. |
| first_indexed | 2024-04-12T03:26:00Z |
| format | Article |
| id | doaj.art-48a0eff3ab1d4cd38407d838faae9d1b |
| institution | Directory Open Access Journal |
| issn | 2057-4967 |
| language | English |
| last_indexed | 2024-04-12T03:26:00Z |
| publishDate | 2017-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Neurosurgical Journal |
| spelling | doaj.art-48a0eff3ab1d4cd38407d838faae9d1b2022-12-22T03:49:41ZengBMCChinese Neurosurgical Journal2057-49672017-07-01311410.1186/s41016-017-0085-4Paediatric intracranial meningiomas: eight-year experience with 32 casesMing-chao Fan0Wei Fang1Ke Liu2Chao Wang3Wen-shuai Deng4Peng Sun5Wan-zhong Tang6Department of Neurological Intensive Care Unit, The Affiliated Hospital of Qingdao UniversityDepartment of Neurological Intensive Care Unit, The Affiliated Hospital of Qingdao UniversityDepartment of Paediatrics, The Affiliated Hospital of Qingdao UniversityDepartment of Neurosurgery, The Affiliated Hospital of Qingdao UniversityDepartment of Neurological Intensive Care Unit, The Affiliated Hospital of Qingdao UniversityDepartment of Neurosurgery, The Affiliated Hospital of Qingdao UniversityDepartment of Neurosurgery, The Affiliated Hospital of Qingdao UniversityAbstract Background The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods We retrospectively reviewed a series of 32 paediatric patients with meningiomas who received surgical resection at the Affiliated Hospital of Qingdao University between January 2002 and December 2010. Results The study group included 17 boys and 15 girls (range: 2–18 years, mean: 13.7 years). Thirteen patients were in the first decade of life and 19 patients were in the second decade. The most common symptoms were headache (33.3%) and epilepsy (25%), followed by cranial nerve dysfunction: distortion of commissure, vision disorder, acoasma and unconsciousness. The size of lesions was ranged 35–65 mm (mean 42.3 mm). Of these 32 patients, 16 were revealed WHO class I meningiomas, 5 were WHO class II, and 11 manifested WHO class III. Nine of 32 patients met the criteria that had tumor recurrence within follow-up. Conclusions Paediatric meningiomas usually have larger size, higher pathologic grade and unusual location. The influential factors for recurrence include lesion location, histological features and extent of removal. Complete tumor resection is the best choice to prevent recurrence and improve the prognosis.http://link.springer.com/article/10.1186/s41016-017-0085-4PaediatricMeningiomaIntracranialCraniotomy |
| spellingShingle | Ming-chao Fan Wei Fang Ke Liu Chao Wang Wen-shuai Deng Peng Sun Wan-zhong Tang Paediatric intracranial meningiomas: eight-year experience with 32 cases Chinese Neurosurgical Journal Paediatric Meningioma Intracranial Craniotomy |
| title | Paediatric intracranial meningiomas: eight-year experience with 32 cases |
| title_full | Paediatric intracranial meningiomas: eight-year experience with 32 cases |
| title_fullStr | Paediatric intracranial meningiomas: eight-year experience with 32 cases |
| title_full_unstemmed | Paediatric intracranial meningiomas: eight-year experience with 32 cases |
| title_short | Paediatric intracranial meningiomas: eight-year experience with 32 cases |
| title_sort | paediatric intracranial meningiomas eight year experience with 32 cases |
| topic | Paediatric Meningioma Intracranial Craniotomy |
| url | http://link.springer.com/article/10.1186/s41016-017-0085-4 |
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