Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice

Extracellular vesicles from IFN-γ-primed mesenchymal stem cells repress atopic dermatitis in mice

Abstract Background Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by immune dysregulation, pruritus, and abnormal epidermal barrier function. Compared with conventional mesenchymal stem cell (MSC), induced pluripotent stem cell (iPSC)-derived mesenchymal stem cell (iMS...

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Bibliographic Details
Main Authors: Jimin Kim, Seul Ki Lee, Minyoung Jung, Seon-Yeong Jeong, Haedeun You, Ji-Yeon Won, Sang-Deok Han, Hye Jin Cho, Somi Park, Joonghoon Park, Tae Min Kim, Soo Kim
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Nanobiotechnology
Subjects:
Atopic dermatitis
iPSC-derived MSC
Extracellular vesicles
IFN-γ
Online Access:https://doi.org/10.1186/s12951-022-01728-8

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