Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes
Summary: The current paradigm indicates that naive T cells are primed in secondary lymphoid organs. Here, we present evidence that intranasal administration of peptide antigens appended to nanofibers primes naive CD8+ T cells in the lung independently and prior to priming in the draining mediastinal...
প্রধান লেখক: | , , , , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Elsevier
2023-10-01
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মালা: | Cell Reports |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | http://www.sciencedirect.com/science/article/pii/S2211124723013116 |