Development of monoclonal antibodies targeting the conserved fragment of hexon protein to detect different serotypes of human adenovirus

Development of monoclonal antibodies targeting the conserved fragment of hexon protein to detect different serotypes of human adenovirus

ABSTRACTHuman adenovirus (HAdV) infects the respiratory system, thus posing a threat to health. However, immunodiagnostic reagents for human adenovirus are limited. This study aimed to develop efficient diagnostic reagents based on monoclonal antibodies for diagnosing various human adenovirus infect...

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Bibliographic Details
Main Authors: Linfan Wu, Yuhao Lin, Juzhen Yin, Changbi Yang, Yushan Jiang, Linlin Zhai, Yuelin Wang, Li Zhu, Qinghua Wu, Bao Zhang, Chengsong Wan, Wei Zhao, Yang Yang, Chenguang Shen, Weiwei Xiao
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
human adenovirus
hexon protein
monoclonal antibodies
ELISA
Western blot
indirect immunofluorescence assay
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01816-23

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