Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers
Objective: Identify symptom clusters based on symptoms experienced by patients with advanced nonsmall cell lung cancers (NSCLCs), and examine the relationship between the symptom clusters and impairment in everyday life and quality of life (QOL). Methods: Using the M.D. Anderson Symptom Inventory, 9...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-01-01
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| Series: | Asia-Pacific Journal of Oncology Nursing |
| Subjects: | |
| Online Access: | http://www.apjon.org/article.asp?issn=2347-5625;year=2016;volume=3;issue=4;spage=370;epage=381;aulast=Hamada |
| _version_ | 1797765805791772672 |
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| author | Tamami Hamada Hiroko Komatsu Margaret Quinn Rosenzweig Naohiko Chohnabayashi Naoki Nishimura Satoshi Oizumi Dianxu Ren |
| author_facet | Tamami Hamada Hiroko Komatsu Margaret Quinn Rosenzweig Naohiko Chohnabayashi Naoki Nishimura Satoshi Oizumi Dianxu Ren |
| author_sort | Tamami Hamada |
| collection | DOAJ |
| description | Objective: Identify symptom clusters based on symptoms experienced by patients with advanced nonsmall cell lung cancers (NSCLCs), and examine the relationship between the symptom clusters and impairment in everyday life and quality of life (QOL). Methods: Using the M.D. Anderson Symptom Inventory, 9 symptom items and the QOL Questionnaire (QLQ-C-30) evaluation apparatus from the European Organization for Research and Treatment of Cancer, we evaluated symptom severity, interference in daily life, and QOL. Factor analysis and multiple regression analysis techniques were used. Results: Sixty patients with advanced NSCLCs seen in pulmonary medicine departments were included in the study. The average age of patients was 64.33 (standard deviation = 11.40). Thirty-six were male and 24 were female. Three symptom clusters were identified as fatigue/anorexia cluster (dry mouth, altered the sense of taste, drowsiness, fatigue/tiredness, and lack of appetite), pain cluster (anxiety, sadness, and pain), numbness cluster (numbness, leg weakness, and distress). The pain cluster had the strongest influence (adjusted R2 = 0.355) on daily life (emotions) while the numbness cluster most strongly affected walking. The fatigue/anorexia cluster explained 22.7% of role function variance. This symptom clustering may be unique among patients with advanced NSCLCs. Conclusions: Each of these clusters affected QOL and everyday life with varying degrees of influence. In clinical screening assessments, focusing on symptom clusters could provide tailored management strategies for patients with advanced NSCLCs. These care strategies may improve outcomes specifically for advanced NSCLCs patients. |
| first_indexed | 2024-03-12T20:15:26Z |
| format | Article |
| id | doaj.art-48a4c6b50a0a4f3b8a40be45dd8212ef |
| institution | Directory Open Access Journal |
| issn | 2347-5625 2349-6673 |
| language | English |
| last_indexed | 2024-03-12T20:15:26Z |
| publishDate | 2016-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asia-Pacific Journal of Oncology Nursing |
| spelling | doaj.art-48a4c6b50a0a4f3b8a40be45dd8212ef2023-08-02T01:21:10ZengElsevierAsia-Pacific Journal of Oncology Nursing2347-56252349-66732016-01-013437038110.4103/2347-5625.196489Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancersTamami HamadaHiroko KomatsuMargaret Quinn RosenzweigNaohiko ChohnabayashiNaoki NishimuraSatoshi OizumiDianxu RenObjective: Identify symptom clusters based on symptoms experienced by patients with advanced nonsmall cell lung cancers (NSCLCs), and examine the relationship between the symptom clusters and impairment in everyday life and quality of life (QOL). Methods: Using the M.D. Anderson Symptom Inventory, 9 symptom items and the QOL Questionnaire (QLQ-C-30) evaluation apparatus from the European Organization for Research and Treatment of Cancer, we evaluated symptom severity, interference in daily life, and QOL. Factor analysis and multiple regression analysis techniques were used. Results: Sixty patients with advanced NSCLCs seen in pulmonary medicine departments were included in the study. The average age of patients was 64.33 (standard deviation = 11.40). Thirty-six were male and 24 were female. Three symptom clusters were identified as fatigue/anorexia cluster (dry mouth, altered the sense of taste, drowsiness, fatigue/tiredness, and lack of appetite), pain cluster (anxiety, sadness, and pain), numbness cluster (numbness, leg weakness, and distress). The pain cluster had the strongest influence (adjusted R2 = 0.355) on daily life (emotions) while the numbness cluster most strongly affected walking. The fatigue/anorexia cluster explained 22.7% of role function variance. This symptom clustering may be unique among patients with advanced NSCLCs. Conclusions: Each of these clusters affected QOL and everyday life with varying degrees of influence. In clinical screening assessments, focusing on symptom clusters could provide tailored management strategies for patients with advanced NSCLCs. These care strategies may improve outcomes specifically for advanced NSCLCs patients.http://www.apjon.org/article.asp?issn=2347-5625;year=2016;volume=3;issue=4;spage=370;epage=381;aulast=HamadaAdvanced nonsmall cell lung cancercross-sectionalfactor analysisimpairment of everyday lifequality of lifesymptom clusters |
| spellingShingle | Tamami Hamada Hiroko Komatsu Margaret Quinn Rosenzweig Naohiko Chohnabayashi Naoki Nishimura Satoshi Oizumi Dianxu Ren Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers Asia-Pacific Journal of Oncology Nursing Advanced nonsmall cell lung cancer cross-sectional factor analysis impairment of everyday life quality of life symptom clusters |
| title | Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| title_full | Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| title_fullStr | Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| title_full_unstemmed | Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| title_short | Impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| title_sort | impact of symptom clusters on quality of life outcomes in patients from japan with advanced nonsmall cell lung cancers |
| topic | Advanced nonsmall cell lung cancer cross-sectional factor analysis impairment of everyday life quality of life symptom clusters |
| url | http://www.apjon.org/article.asp?issn=2347-5625;year=2016;volume=3;issue=4;spage=370;epage=381;aulast=Hamada |
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