Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice

Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice

Voglibose is an α-glycosidase inhibitor that improves postprandial hyperglycemia and increases glucagon-like peptide-1 (GLP-1) secretion in patients with type 2 diabetes. Recently, there has been increasing interest in the anti-inflammatory effects of voglibose on the intestine, but the underlying m...

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Bibliographic Details
Main Authors: Yaxin Fu, Wenming Ji, Quan Liu, Lin Zhang, Caina Li, Yi Huan, Lei Lei, Xuefeng Gao, Leilei Chen, Cunyu Feng, Liran Lei, Jiayu Zhai, Pingping Li, Hui Cao, Shuainan Liu, Zhufang Shen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
voglibose
type 2 diabetes
inflammation
ileal macrophages
endoplasmic reticulum stress
Online Access:https://www.mdpi.com/1422-0067/23/24/15938

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