The critical role of DNA extraction for detection of mycobacteria in tissues.
BACKGROUND:Nucleic acid-based methods offer promise for both targeted and exploratory investigations of microbes in tissue samples. As the starting material for such studies is a mixture of host and microbial DNA, we have critically evaluated the DNA extraction step to determine the quantitative and...
Main Authors: | Nicolas Radomski, Louis Kreitmann, Fiona McIntosh, Marcel A Behr |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3806855?pdf=render |
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