THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN
Flavonoids and phenolics are compounds with hydroxyl groups (-OH) bound to aromatic rings which enable them to react with reactive oxygen species and eliminate free radical activity. Single bulb garlic (Allium sativum var. solo garlic) is known to have antioxidant activity which comes from the pheno...
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| Format: | Article |
| Language: | English |
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Universitas Sanata Dharma
2020-01-01
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| Series: | Jurnal Farmasi Sains dan Komunitas |
| Subjects: | |
| Online Access: | https://e-journal.usd.ac.id/index.php/JFSK/article/view/1798 |
| _version_ | 1818287677414309888 |
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| author | Ika Buana Januarti Hudan Taufiq Sulistyaningsih Sulistyaningsih |
| author_facet | Ika Buana Januarti Hudan Taufiq Sulistyaningsih Sulistyaningsih |
| author_sort | Ika Buana Januarti |
| collection | DOAJ |
| description | Flavonoids and phenolics are compounds with hydroxyl groups (-OH) bound to aromatic rings which enable them to react with reactive oxygen species and eliminate free radical activity. Single bulb garlic (Allium sativum var. solo garlic) is known to have antioxidant activity which comes from the phenolic groups. This study aims to determine the correlation of total flavonoid and phenolic levels with the antioxidant activity of ethanolic extracts from single bulb garlic grown in Magetan and Tawangmangu regions. This study included an observational analytic study with a cross-sectional design. Total flavonoid levels were measured by colorimetric method and total phenolic levels were measured by Folin-ciocalteu method using Spectrophotometric UV-Vis. Antioxidant activity was measured by DPPH method at a wavelength of 517 nm. The data analysis used was multiple linear regression. The results showed that the extract of single bulb garlic from Magetan had total flavonoids of 12,1833 ± 0,1943 mg QE/gram, total phenolics of 70,244 mg GAE/gram, and antioxidant activity with an IC50 value of 20,216 ppm. The extract of single bulb garlic from Tawangmangu contained total flavonoids of 14,4833 ± 0,5911 mg QE/gram, total phenolics of 92,222 mg GAE/gram, and antioxidant activity with an IC50 value of 13,777 ppm. The conclusion of this study is that there is a significant correlation of total flavonoid and total phenolic content with antioxidant activity. |
| first_indexed | 2024-12-13T01:44:17Z |
| format | Article |
| id | doaj.art-48a8486bc3ad4e7682262a90365bfecf |
| institution | Directory Open Access Journal |
| issn | 1693-5683 2527-7146 |
| language | English |
| last_indexed | 2024-12-13T01:44:17Z |
| publishDate | 2020-01-01 |
| publisher | Universitas Sanata Dharma |
| record_format | Article |
| series | Jurnal Farmasi Sains dan Komunitas |
| spelling | doaj.art-48a8486bc3ad4e7682262a90365bfecf2022-12-22T00:03:40ZengUniversitas Sanata DharmaJurnal Farmasi Sains dan Komunitas1693-56832527-71462020-01-011629610310.24071/jpsc.0017981536THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETANIka Buana Januarti0Hudan Taufiq1Sulistyaningsih Sulistyaningsih2Universitas Islam Sultan AgungUniversitas Islam Sultan AgungUniversitas Islam Sultan AgungFlavonoids and phenolics are compounds with hydroxyl groups (-OH) bound to aromatic rings which enable them to react with reactive oxygen species and eliminate free radical activity. Single bulb garlic (Allium sativum var. solo garlic) is known to have antioxidant activity which comes from the phenolic groups. This study aims to determine the correlation of total flavonoid and phenolic levels with the antioxidant activity of ethanolic extracts from single bulb garlic grown in Magetan and Tawangmangu regions. This study included an observational analytic study with a cross-sectional design. Total flavonoid levels were measured by colorimetric method and total phenolic levels were measured by Folin-ciocalteu method using Spectrophotometric UV-Vis. Antioxidant activity was measured by DPPH method at a wavelength of 517 nm. The data analysis used was multiple linear regression. The results showed that the extract of single bulb garlic from Magetan had total flavonoids of 12,1833 ± 0,1943 mg QE/gram, total phenolics of 70,244 mg GAE/gram, and antioxidant activity with an IC50 value of 20,216 ppm. The extract of single bulb garlic from Tawangmangu contained total flavonoids of 14,4833 ± 0,5911 mg QE/gram, total phenolics of 92,222 mg GAE/gram, and antioxidant activity with an IC50 value of 13,777 ppm. The conclusion of this study is that there is a significant correlation of total flavonoid and total phenolic content with antioxidant activity.https://e-journal.usd.ac.id/index.php/JFSK/article/view/1798antioxidantflavonoidgarlicphenolic |
| spellingShingle | Ika Buana Januarti Hudan Taufiq Sulistyaningsih Sulistyaningsih THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN Jurnal Farmasi Sains dan Komunitas antioxidant flavonoid garlic phenolic |
| title | THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN |
| title_full | THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN |
| title_fullStr | THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN |
| title_full_unstemmed | THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN |
| title_short | THE CORRELATION OF TOTAL FLAVONOID AND TOTAL PHENOLIC WITH ANTIOXIDANT ACTIVITY OF SINGLE BULB GARLIC (Allium Sativum) FROM TAWANGMANGU AND MAGETAN |
| title_sort | correlation of total flavonoid and total phenolic with antioxidant activity of single bulb garlic allium sativum from tawangmangu and magetan |
| topic | antioxidant flavonoid garlic phenolic |
| url | https://e-journal.usd.ac.id/index.php/JFSK/article/view/1798 |
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