Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human

Transcriptomics-driven metabolic pathway analysis reveals similar alterations in lipid metabolism in mouse MASH model and human

Abstract Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent chronic liver disease worldwide, and can rapidly progress to metabolic dysfunction-associated steatohepatitis (MASH). Accurate preclinical models and methodologies are needed to understand underlying...

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Bibliographic Details
Main Authors: Sofia Tsouka, Pavitra Kumar, Patcharamon Seubnooch, Katrin Freiburghaus, Marie St-Pierre, Jean-François Dufour, Mojgan Masoodi
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00465-3

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