In Vivo Assessment of Zearalenone Toxicity

The microscopic filamentous fungi of the genus Fusarium are capable of producing secondary metabolites—mycotoxins. Fusarium fungi synthesize trichothecenes, zearalenone (ZEA) and fumonisins under appropriate environmental conditions. In this biological experiment, we studied the effects of zearaleno...

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Main Authors: Harčárová M., Čonková E., Proškovcová M., Falis M.
Format: Article
Language:English
Published: Sciendo 2020-06-01
Series:Folia Veterinaria
Subjects:
Online Access:https://doi.org/10.2478/fv-2020-0018
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author Harčárová M.
Čonková E.
Proškovcová M.
Falis M.
author_facet Harčárová M.
Čonková E.
Proškovcová M.
Falis M.
author_sort Harčárová M.
collection DOAJ
description The microscopic filamentous fungi of the genus Fusarium are capable of producing secondary metabolites—mycotoxins. Fusarium fungi synthesize trichothecenes, zearalenone (ZEA) and fumonisins under appropriate environmental conditions. In this biological experiment, we studied the effects of zearalenone on a model organism called Artemia franciscana. During the three-day in vivo tests, we used five different concentrations of zearalenone (0.08 ppm, 0.4 ppm, 2 ppm, 10 ppm and 50 ppm). The results of this study showed that as the zearalenone concentration and the duration of the mycotoxin exposure increased, the lethality of artemia also increased. Our study showed that the toxicity of zearalenone to Artemia franciscana was relatively low.
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spelling doaj.art-48aaa1b9ba164730be840030adf049172022-12-21T20:03:39ZengSciendoFolia Veterinaria2453-78372020-06-01642606510.2478/fv-2020-0018fv-2020-0018In Vivo Assessment of Zearalenone ToxicityHarčárová M.0Čonková E.1Proškovcová M.2Falis M.3Institute of nutrition, dietetics and feed productionInstitute of pharmacologyInstitute of pharmacologyInstitute of toxicology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81KošiceSlovakiaThe microscopic filamentous fungi of the genus Fusarium are capable of producing secondary metabolites—mycotoxins. Fusarium fungi synthesize trichothecenes, zearalenone (ZEA) and fumonisins under appropriate environmental conditions. In this biological experiment, we studied the effects of zearalenone on a model organism called Artemia franciscana. During the three-day in vivo tests, we used five different concentrations of zearalenone (0.08 ppm, 0.4 ppm, 2 ppm, 10 ppm and 50 ppm). The results of this study showed that as the zearalenone concentration and the duration of the mycotoxin exposure increased, the lethality of artemia also increased. Our study showed that the toxicity of zearalenone to Artemia franciscana was relatively low.https://doi.org/10.2478/fv-2020-0018artemia franciscanain vivotoxicityzearalenone
spellingShingle Harčárová M.
Čonková E.
Proškovcová M.
Falis M.
In Vivo Assessment of Zearalenone Toxicity
Folia Veterinaria
artemia franciscana
in vivo
toxicity
zearalenone
title In Vivo Assessment of Zearalenone Toxicity
title_full In Vivo Assessment of Zearalenone Toxicity
title_fullStr In Vivo Assessment of Zearalenone Toxicity
title_full_unstemmed In Vivo Assessment of Zearalenone Toxicity
title_short In Vivo Assessment of Zearalenone Toxicity
title_sort in vivo assessment of zearalenone toxicity
topic artemia franciscana
in vivo
toxicity
zearalenone
url https://doi.org/10.2478/fv-2020-0018
work_keys_str_mv AT harcarovam invivoassessmentofzearalenonetoxicity
AT conkovae invivoassessmentofzearalenonetoxicity
AT proskovcovam invivoassessmentofzearalenonetoxicity
AT falism invivoassessmentofzearalenonetoxicity