Eltrombopag for Adults and Children with Immune-Refractory Thrombocytopenic Purpura: A Systematic Review

Eltrombopag for Adults and Children with Immune-Refractory Thrombocytopenic Purpura: A Systematic Review

Eltrombopag is an agonist that binds to the membrane-bound domain of the thrombopoietin receptor used in immune thrombocytopenic purpura (ITP). We conducted a meta-analysis of randomized controlled trials to assess the efficacy and safety of eltrombopag in adults and children with refractory ITP. Ad...

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Bibliographic Details
Main Authors: Danielle Francisco Honorato de Barros Torelli, Crystian Bitencourt Soares Oliveira, Gisele Alborghetti Nai, Evelinda Marramon Trindade, Luiz Euribel Prestes-Carneiro
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Journal of Clinical Medicine
Subjects:
immune thrombocytopenic purpura
erythropoietin receptors
systematic review
blood coagulation
hematologic drugs
Online Access:https://www.mdpi.com/2077-0383/12/12/3872

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