Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats

Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats

Abstract Background Dietary protein deficiency and amino acid imbalance cause hepatic fat accumulation. We previously demonstrated that only arginine deficiency or total amino acid deficiency in a diet caused significant hepatic triglyceride (TG) accumulation in young Wistar rats. In this study, we...

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Bibliographic Details
Main Authors: Lila Otani, Hiroki Nishi, Ayaka Koyama, Yuta Akasaka, Yusuke Taguchi, Yuka Toyoshima, Daisuke Yamanaka, Fumihiko Hakuno, Huijuan Jia, Shin-Ichiro Takahashi, Hisanori Kato
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Nutrition & Metabolism
Subjects:
Arginine deficiency
Low-protein diet
Hepatosteatosis
Apolipoprotein A-IV
Insulin signaling
Online Access:http://link.springer.com/article/10.1186/s12986-020-00477-5

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