Primary gastric Ewing sarcoma/primitive neuroectodermal tumor
A rare and highly malignant small round cell tumor, Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) usually occurs in the pelvis, long-axis bones, and femur. In contrast, extraosseous ES is more often found in the paraspinal region, limbs, and retroperitoneum, but is extremely rare in the st...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-02-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060520986681 |
| _version_ | 1819290145568849920 |
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| author | Yu Ye Xiaoming Qiu Jixin Mei Dongyun He Ailing Zou |
| author_facet | Yu Ye Xiaoming Qiu Jixin Mei Dongyun He Ailing Zou |
| author_sort | Yu Ye |
| collection | DOAJ |
| description | A rare and highly malignant small round cell tumor, Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) usually occurs in the pelvis, long-axis bones, and femur. In contrast, extraosseous ES is more often found in the paraspinal region, limbs, and retroperitoneum, but is extremely rare in the stomach. We report a case of a 55-year-old woman who presented with fatigue, fever, and black stool. Preoperative computed tomography (CT) imaging showed a large ulcerative lesion of approximately 5.5 × 5.0 cm in the stomach and irregular thickening of the ulcer wall. Upper endoscopy revealed a large, irregular ulcer in the posterior wall of the stomach. Histopathological examination suggested that the mass with the largest diameter (7.5 cm) was ES. Immunohistochemistry indicated positivity for CD99. Enhanced CT of the whole body was performed but no definite masses were found in other organs, and the patient was diagnosed with primary gastric ES. The patient underwent radical distal gastrectomy with Roux-en-Y gastrojejunostomy, but refused chemoradiotherapy. |
| first_indexed | 2024-12-24T03:18:05Z |
| format | Article |
| id | doaj.art-48b74de224ff49de9adbdfa773d59c34 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-12-24T03:18:05Z |
| publishDate | 2021-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-48b74de224ff49de9adbdfa773d59c342022-12-21T17:17:34ZengSAGE PublishingJournal of International Medical Research1473-23002021-02-014910.1177/0300060520986681Primary gastric Ewing sarcoma/primitive neuroectodermal tumorYu YeXiaoming QiuJixin MeiDongyun HeAiling ZouA rare and highly malignant small round cell tumor, Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) usually occurs in the pelvis, long-axis bones, and femur. In contrast, extraosseous ES is more often found in the paraspinal region, limbs, and retroperitoneum, but is extremely rare in the stomach. We report a case of a 55-year-old woman who presented with fatigue, fever, and black stool. Preoperative computed tomography (CT) imaging showed a large ulcerative lesion of approximately 5.5 × 5.0 cm in the stomach and irregular thickening of the ulcer wall. Upper endoscopy revealed a large, irregular ulcer in the posterior wall of the stomach. Histopathological examination suggested that the mass with the largest diameter (7.5 cm) was ES. Immunohistochemistry indicated positivity for CD99. Enhanced CT of the whole body was performed but no definite masses were found in other organs, and the patient was diagnosed with primary gastric ES. The patient underwent radical distal gastrectomy with Roux-en-Y gastrojejunostomy, but refused chemoradiotherapy.https://doi.org/10.1177/0300060520986681 |
| spellingShingle | Yu Ye Xiaoming Qiu Jixin Mei Dongyun He Ailing Zou Primary gastric Ewing sarcoma/primitive neuroectodermal tumor Journal of International Medical Research |
| title | Primary gastric Ewing sarcoma/primitive neuroectodermal tumor |
| title_full | Primary gastric Ewing sarcoma/primitive neuroectodermal tumor |
| title_fullStr | Primary gastric Ewing sarcoma/primitive neuroectodermal tumor |
| title_full_unstemmed | Primary gastric Ewing sarcoma/primitive neuroectodermal tumor |
| title_short | Primary gastric Ewing sarcoma/primitive neuroectodermal tumor |
| title_sort | primary gastric ewing sarcoma primitive neuroectodermal tumor |
| url | https://doi.org/10.1177/0300060520986681 |
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