A live-attenuated viral vector vaccine protects mice against lethal challenge with Kyasanur Forest disease virus

Abstract Kyasanur Forest disease virus (KFDV) is a tick-borne flavivirus endemic in India known to cause severe hemorrhagic and encephalitic disease in humans. In recent years, KFDV has spread beyond its original endemic zone raising public health concerns. Currently, there is no treatment available...

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Bibliographic Details
Main Authors: Bharti Bhatia, Kimberly Meade-White, Elaine Haddock, Friederike Feldmann, Andrea Marzi, Heinz Feldmann
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00416-2