Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus

Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus

Abstract The biosynthesis of host lipids and/or lipid droplets (LDs) has been studied extensively as a putative therapeutic target in diverse viral infections. However, directly targeting the LD lipolytic catabolism in virus-infected cells has not been widely investigated. Here, we show the linkage...

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Bibliographic Details
Main Authors: Yeong-Bin Baek, Hyung-Jun Kwon, Muhammad Sharif, Jeongah Lim, In-Chul Lee, Young Bae Ryu, Jae-In Lee, Ji-Sun Kim, Young-Seung Lee, Dong-Hoon Kim, Sang-Ik Park, Don-Kyu Kim, Jeong-Sun Kim, Hyon E. Choy, Sunwoo Lee, Hueng-Sik Choi, Timothy F. Osborne, Tae-Il Jeon, Kyoung-Oh Cho
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01223-4

Internet

https://doi.org/10.1038/s41392-022-01223-4

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