Ascending Axonal Degeneration of the Corticospinal Tract in Pure Hereditary Spastic Paraplegia: A Cross-Sectional DTI Study

Ascending Axonal Degeneration of the Corticospinal Tract in Pure Hereditary Spastic Paraplegia: A Cross-Sectional DTI Study

Objective: To identify structural white matter alterations in patients with pure hereditary spastic paraplegia (HSP) using high angular resolution diffusion tensor imaging (DTI). Methods: We examined 37 individuals with high resolution DTI, 20 patients with pure forms of hereditary spastic paraplegi...

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Bibliographic Details
Main Authors: Julia List, Zacharias Kohl, Juergen Winkler, Franz Marxreiter, Arnd Doerfler, Manuel A. Schmidt
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Brain Sciences
Subjects:
hereditary spastic paraplegia
diffusion tensor imaging
fractional anisotropy
tract-based spatial statistics (tbss)
corticospinal tract
Online Access:https://www.mdpi.com/2076-3425/9/10/268

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